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- Table of Contents
Heat shock protein beta-6 Antibodies
AND HSPB6 ELISA kits, Heat shock protein beta-6 Proteins
Many biological assays use antibodies to detect Heat shock protein beta-6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Heat shock protein beta-6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Heat shock protein beta-6 antibodies...
Designing a Western blot for Heat shock protein beta-6? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HSPB6 Western Blot GuideDesigning an IHC experiment for Heat shock protein beta-6? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the HSPB6 IHC GuideHSPB6 Infographic by Boster Bio
All HSPB6 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # A07981-1
100 μg/vial
Cat # A07981-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M07981
100 μl
Cat # M07981
100 μl
HSPB6 Overview
Facts about Heat shock protein beta-6.
Heat shock protein beta-6 (HSPB6)
Small heat shock protein which functions as a molecular chaperone probably keeping denatured proteins in a folding- competent state. Seems to have versatile functions in various biological processes.
Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR.
Gene Information
| Human | |
|---|---|
| Gene Name: | HSPB6 |
| Uniprot: | O14558 |
| Entrez: | 126393 |
Family
| Belongs to: |
|---|
| small heat shock protein (HSP20) family |
Alternative Names
FLJ32389; Heat shock 20 kDa-like protein p20; heat shock protein beta-6; heat shock protein, alpha-crystallin-related, B6; HSP20; HSPB6
Molecular Weight
Mass (kDA):
17.136 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.12 |
| Sequence: | 19; NC_000019.10 (35754566..35757029, complement) |
Subcellular Localizations
Cytoplasm. Nucleus. Secreted. Translocates to nuclear foci during heat shock.
Diseases
- Observation Of Neuromuscular Block
- Hypertrophy
- Vasospasm
- Dystrophy
- Reperfusion Injury
- Malignant Neoplasms
- Pathologic Vasoconstriction
- Physiological Stress
- Heart Diseases
- Myocardial Infarction
- Cardiomyopathies
- Thrombosis
- Alzheimer's Disease
Interacting Proteins
- HSPB8
Pathways
- Platelet Aggregation
- Muscle Contraction
- Smooth Muscle Contraction
- Relaxation Of Vascular Smooth Muscle
- Proteolysis
- Cell Death
- Tube Formation
- Regulation Of Smooth Muscle Contraction
- Protein Folding
- Angiogenesis
- Autophagy
- Transport
- Vascular Smooth Muscle Contraction
PTMs
- Phosphorylation
- Dephosphorylation
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HSPB6
bosterbio.com/bosterbio-gene-info-cards/HSPB6
References
PMID: 8195168 by Kato K., et al. Purification and characterization of a 20-kDa protein that is highly homologous to alpha B crystallin.
PMID: 19845507 by Fuchs M., et al. Identification of the key structural motifs involved in HspB8/HspB6- Bag3 interaction.