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- Table of Contents
IGFBP5 Antibodies
AND IGFBP5 ELISA kits, IGFBP5 Proteins
Many biological assays use antibodies to detect IGFBP5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IGFBP5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IGFBP5 antibodies...
Designing a Western blot for IGFBP5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IGFBP5 Western Blot GuideIGFBP5 Infographic by Boster Bio
All IGFBP5 Products
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Specificity
Applications
Price
IGFBP5 Overview
Facts about Insulin-like growth factor-binding protein 5.
Insulin-like growth factor-binding protein 5 (IGFBP5)
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
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Gene Information
| Human | |
|---|---|
| Gene Name: | IGFBP5 |
| Uniprot: | P24593 |
| Entrez: | 3488 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
IBP5IBP-5; IGF-binding protein 5; IGFBP5; IGFBP-5; insulin-like growth factor binding protein 5; insulin-like growth factor-binding protein 5
Molecular Weight
Mass (kDA):
30.57 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q35 |
| Sequence: | 2; NC_000002.12 (216672105..216695549, complement) |
Tissue Specificity
Osteosarcoma, and at lower levels in liver, kidney and brain.
Subcellular Localizations
Secreted.
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Carcinoma
- Neoplasm Metastasis
- Cell Transformation, Neoplastic
- Cell Invasion
- Hypertrophy
- Tissue Adhesions
- Malignant Neoplasm Of Prostate
- Fibrosis
- Diabetes Mellitus
Pathways
- Cell Proliferation
- Secretion
- Pathogenesis
- Cell Cycle
- Lactation
- Cell Death
- Cell Growth
- Cell Adhesion
- Cell Differentiation
- Localization
- Angiogenesis
- Cell Migration
- Regeneration
PTMs
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IGFBP5
bosterbio.com/bosterbio-gene-info-cards/IGFBP5
References
PMID: 1850258 by Kiefer M.C., et al. Molecular cloning of a new human insulin-like growth factor binding protein.
PMID: 1709938 by Shimasaki S., et al. Identification of five different insulin-like growth factor binding proteins (IGFBPs) from adult rat serum and molecular cloning of a novel IGFBP-5 in rat and human.
6 Publications of Boster IGFBP5 Antibodies & ELISA Kits
- PubMed ID: 10.1007/s11626-016-0109-y, miR-143 regulates proliferation and differentiation of bovine skeletal muscle sa...
- PubMed ID: 30482199 , Chi-miR-3031 regulates beta-casein via the PI3K/AKT-mTOR signaling pathway in go...
- PubMed ID: 20003295, The effects of HIF-1alpha on gene expression profiles of NCI-H446 human small ce...
- PubMed ID: 19476635, Expressions of IGFBP-5, cFLIP in cervical intraepithelial neoplasia, cervical ca...
- PubMed ID: 2797501, The effects of HIF-1alpha on gene expression profiles of NCI-H446 human small ce...
- PubMed ID: 2698862, Expressions of IGFBP-5, cFLIP in cervical intraepithelial neoplasia, cervical ca...
*More publications can be found for each product on its corresponding product page