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- Table of Contents
IL6R Antibodies
AND IL6R ELISA kits, IL6R Proteins
Many biological assays use antibodies to detect IL6R, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IL6R in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IL6R antibodies...
Designing a Western blot for IL6R? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IL6R Western Blot GuideIL6R Infographic by Boster Bio
All IL6R Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0777
96 wells/kit, with removable strips.
Cat # EK0777
96 wells/kit, with removable strips.
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01425-2
100 μg
Cat # M01425-2
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00102-7
100 μg
Cat # M00102-7
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01425-6
100 μg
Cat # M01425-6
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01425-5
100 μg
Cat # M01425-5
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01425-4
100 μg
Cat # M01425-4
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01425-3
100 μg
Cat # M01425-3
100 μg
IL6R Overview
Facts about Interleukin-6 receptor subunit alpha.
Interleukin-6 receptor subunit alpha (IL6R)
Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but doesn't transduce a signal.
Signal activation necessitate an association with IL6ST. Activation can lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
Gene Information
| Human | |
|---|---|
| Gene Name: | IL6R |
| Uniprot: | P08887 |
| Entrez: | 3570 |
Family
| Belongs to: |
|---|
| type I cytokine receptor family |
Alternative Names
CD126; gp80; IL-6 R alpha; IL6Q; IL6R alpha; IL-6R alpha; IL6R; IL-6R-1; IL6RA; IL-6Ra; IL6RQ; interleukin 6 receptor
Molecular Weight
Mass (kDA):
51.548 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q21.3 |
| Sequence: | 1; NC_000001.11 (154405193..154469450) |
Tissue Specificity
Isoform 2 is expressed in peripheral blood mononuclear cells and weakly found in urine and serum.
Subcellular Localizations
[Isoform 1]: Basolateral cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
Diseases
- Inflammation
- Malignant Neoplasms
- Rheumatoid Arthritis
- Diabetes Mellitus
- Arthritis
- Neoplasms
- Diabetes Mellitus, Non-insulin-dependent
- Cardiovascular Diseases
- Obesity
- Dysequilibrium Syndrome
- Carcinoma
- Atherosclerosis
- Liver Carcinoma
Interacting Proteins
- IL6
- PSMD9
Pathways
- Pathogenesis
- Immune Response
- Inflammatory Response
- Cell Proliferation
- Secretion
- Cell Growth
- Transport
- Aging
- Interleukin-6 Production
- Cell Cycle
- Innate Immune Response
- Localization
- Cytokine Production
PTMs
- Phosphorylation
- Cleavage
- Biotinylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL6R
bosterbio.com/bosterbio-gene-info-cards/IL6R
References
PMID: 3136546 by Yamasaki K., et al. Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor.
PMID: 1872801 by Schooltink H., et al. Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells.
3 Publications of Boster IL6R Antibodies & ELISA Kits
- PubMed ID: 10.3389/fphar.2021.766909, Beta-Lapachone Attenuates BMSC-Mediated Neuroblastoma Malignant Transformation b...
- PubMed ID: 10.1155/2018/3928915, The Role of IL-6RA in UHMWPE Promotes Proliferation in Fibro-Like Synovial Cells
- PubMed ID: 30426007, The Role of IL-6RA in UHMWPE Promotes Proliferation in Fibro-Like Synovial Cells
*More publications can be found for each product on its corresponding product page