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- Table of Contents
Facts about Ras GTPase-activating-like protein IQGAP2.
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Human | |
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Gene Name: | IQGAP2 |
Uniprot: | Q13576 |
Entrez: | 10788 |
Belongs to: |
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No superfamily |
IQ motif containing GTPase activating protein 2; IQGAP2; ras GTPase-activating-like protein IQGAP2
Mass (kDA):
180.578 kDA
Human | |
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Location: | 5q13.3 |
Sequence: | 5; NC_000005.10 (76403285..76708132) |
The IQGAP2 Marker is an enzyme that is encoded by a gene in both mice and humans. Scientists worldwide can submit their results for the specific species and applications they are working with. Boster scientists can earn product credits for their findings. This is beneficial to scientists of all disciplines. Boster scientists can use this marker to analyze their samples and obtain the results they need.
The IQGAP2 gene is a member of the Ras GTPase-activating-like protein family. It is an enzyme that interacts with signaling molecules and cell adhesion molecules. The gene also undergoes alternative splicing, leading to multiple transcript variants. It is considered a tumor suppressor and acts on several biological pathways. Boster Bio's IQGAP2 antibody is validated using multiple methods and is available in a convenient reagent kit.
The IQGAP2 marker is a member of the Ras GTPase-activating protein family, with three IQ domains, one calponin homology domain, and one Ras-GAP domain. It binds to a variety of cell adhesion and signaling molecules. IQGAP2 is an important tumor suppressor. The gene for IQGAP2 is frequently alternatively spliced, resulting in multiple transcript variants. IQGAP2 has a specialized role in tumor suppressor biology, wherein it interacts with cell adhesion and signaling molecules.
PMID: 8756646 by Brill S., et al. The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases.