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IRAK3 Antibodies

AND IRAK3 ELISA kits, IRAK3 Proteins

Many biological assays use antibodies to detect IRAK3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IRAK3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IRAK3 antibodies...

We validate the specificity of these antibodies to IRAK3 by testing them on tissues known to express IRAK3 positively and negatively. Browse below to find the IRAK3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IRAK3 Infographic by Boster Bio

IRAK3 protein infographic

All IRAK3 Products

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Product

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Specificity

Applications

Price

Anti-IRAKM/IRAK3 Antibody Picoband®

Anti-IRAKM antibody, PA2207-1, Western blottingLane 1: HELA Cell LysateLane 2: JURKAT Cell LysateLane 3: HUT102 Cell Lysate

Anti-IRAKM antibody, PA2207-1, Western blottingLane 1: HELA Cell LysateLane 2: JURKAT Cell LysateLane 3: HUT102 Cell Lysate

Human

WB

$370
Cat # PA2207-1
100 μg/vial

Anti-IRAK3/Irak M Rabbit Monoclonal Antibody

5 Q&As

Western blot analysis of SGK1 expression in A431 cell lysate

Western blot analysis of SGK1 expression in A431 cell lysate

Human

IP, WB

$370
Cat # M02469
100 μl

IRAKM (IRAK3) (NM_007199) Human Over-expression Lysate

IRAKM (IRAK3) Human Over-expression Lysates NM_001142523

IRAKM (IRAK3) Human Over-expression Lysates NM_001142523

IRAKM (IRAK3) Human Over-expression Lysates NM_007199

Human

$628
Cat # LS011213
20 µg, 100 µg

IRAK3 Overview

Facts about Interleukin-1 receptor-associated kinase 3.

IRAK3 3D structure

IRAK3 3D structure. Source: alphafold

Interleukin-1 receptor-associated kinase 3 (IRAK3)

Inhibits dissociation of IRAK1 and IRAK4 from the Toll- like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. .

Gene Information

Human
Gene Name:	IRAK3
Uniprot:	Q9Y616
Entrez:	11213

Gene Information

Family

Belongs to:

protein kinase superfamily

Family

Alternative Names

ASRT5; EC 2.7.11.1; FLJ13601; IL-1 receptor-associated kinase M; interleukin-1 receptor-associated kinase 3; IRAK3; IRAK-3; IRAKM; IRAK-M

Molecular Weight

Mass (kDA):
67.767 kDA

Molecular Weight

Genomic Context


Human

Location:	12q14.3
Sequence:	12; NC_000012.12 (66189214..66254622)

Tissue Specificity

Expressed predominantly in peripheral blood lymphocytes.

Diseases

Inflammation
Inflammatory Response
Innate Immune Response
Malignant Neoplasms
Systemic Infection
Neoplasms
Infective Disorder
Pneumonia
Asthma
Respiratory Tract Infections
Lung Injury
Acute Lung Injury
Tissue Adhesions

Decreased Immunologic Activity [pe]
Neoplasm Metastasis
Injury To Liver
Osteoporosis
Bacterial Infections
Leukemia
Tumor Angiogenesis

Disease

Pathways

Immune Response
Inflammatory Response
Cytokine Production
Pathogenesis
Innate Immune Response
Rna Interference
Secretion
Virulence
Sensitization
Phagocytosis
Bone Development
Macrophage Activation
Angiogenesis

Cell Adhesion
Osteoclast Differentiation
Cell Activation
Cell Migration
Diapedesis
Response To Virus
Adaptive Immune Response

Pathways

PTMs

Phosphorylation
Acetylation

Cleavage
Methylation

Research Areas

Immunology
Innate Immunity
Protein Kinase

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IRAK3

References

PMID: 10383454 by Wesche H., et al. IRAK-M is a novel member of the Pelle/interleukin-1 receptor- associated kinase (IRAK) family.

PMID: 17503328 by Balaci L., et al. IRAK-M is involved in the pathogenesis of early-onset persistent asthma.