This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Integrin alpha-2 Antibodies
AND ITGA2 ELISA kits, Integrin alpha-2 Proteins
Many biological assays use antibodies to detect Integrin alpha-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-2 antibodies...
Designing a Western blot for Integrin alpha-2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ITGA2 Western Blot GuideITGA2 Infographic by Boster Bio
All ITGA2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$370
Cat # PB9647
100 μg/vial
Cat # PB9647
100 μg/vial
Human, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01102-1
100 µg/vial
Cat # A01102-1
100 µg/vial
Anti-Integrin alpha 2/ITGA2 Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, WB
$370
Cat # A01933-2
100 μg/vial
Cat # A01933-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01933
100 μl
Cat # M01933
100 μl
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01933-2
100 μg
Cat # M01933-2
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01933-1
100 μg
Cat # M01933-1
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01102-4
100 μg
Cat # M01102-4
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01102-3
100 μg
Cat # M01102-3
100 μg
Human, Primate
Flow Cytometry, IHC-F
$301
Cat # M01102-1
0.1 mg
Cat # M01102-1
0.1 mg
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$405
Cat # A01933-1
100ul
Cat # A01933-1
100ul
ITGA2 Overview
Facts about Integrin alpha-2.
Integrin alpha-2 (ITGA2)
Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It admits the proline-hydroxylated sequence G-F-P-G-E-R in hydration.
It's responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGA2 |
| Uniprot: | P17301 |
| Entrez: | 3673 |
Family
| Belongs to: |
|---|
| integrin alpha chain family |
Alternative Names
alpha-2 subunit; CD49b antigen; CD49b; Integrin alpha 2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); ITGA2; VLA 2; VLA-2 alpha
Molecular Weight
Mass (kDA):
129.295 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q11.2 |
| Sequence: | 5; NC_000005.10 (52989352..53094779) |
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Malignant Neoplasms
- Cerebrovascular Accident
- Neoplasms
- Diabetes Mellitus
- Neoplasm Metastasis
- Ischemic Stroke
- Hemorrhage
- Thrombosis
- Carcinoma
- 5,10-methylenetetrahydrofolate Reductase Deficiency
- Diabetes Mellitus, Non-insulin-dependent
- Inflammation
Interacting Proteins
- Ap2m1
- ITGB1
- KDR
- Rab21
- SHARPIN
Pathways
- Pathogenesis
- Cell Adhesion
- Hemostasis
- Coagulation
- Immune Response
- Platelet Aggregation
- Inflammatory Response
- Localization
- Cell Growth
- Osteoblast Differentiation
- Fibroblast Proliferation
- Lymphangiogenesis
- Mrna Splicing
PTMs
- Demethylation
Research Areas
- Cellular Markers
- Innate Immunity
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGA2
bosterbio.com/bosterbio-gene-info-cards/ITGA2
References
PMID: 2545729 by Takada Y., et al. The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.
PMID: 8276836 by Zutter M.M., et al. The human alpha 2 integrin gene promoter. Identification of positive and negative regulatory elements important for cell-type and developmentally restricted gene expression.
3 Publications of Boster Integrin alpha-2 Antibodies & ELISA Kits
- PubMed ID: 10.1038/s41598-017-12073-4, Thrombopoietic stimulating activity of rhTyrRS (Y341A)
- PubMed ID: -, Leila Revollo,Glenn Merrill-Skoloff,Karen De Ceunynck,James Dilks,Mattia Bordoli...
- PubMed ID: 28939876, Thrombopoietic stimulating activity of rhTyrRS (Y341A)
*More publications can be found for each product on its corresponding product page