ITPR3 Antibodies

AND ITPR3 ELISA kits, ITPR3 Proteins

Many biological assays use antibodies to detect ITPR3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ITPR3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ITPR3 antibodies...

We validate the specificity of these antibodies to ITPR3 by testing them on tissues known to express ITPR3 positively and negatively. Browse below to find the ITPR3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ITPR3 Infographic by Boster Bio

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Anti-ITPR3 Antibody Picoband®

1 Citations 7 Q&As

Western blot analysis of ITPR3 using anti-ITPR3 antibody (PB9428)

IHC analysis of ITPR3 using anti-ITPR3 antibody (PB9428)

Human, Mouse, Rat

IHC, WB

$370
Cat # PB9428
100 μg/vial

ITPR3 Overview

Facts about Inositol 1,4,5-trisphosphate receptor type 3.

ITPR3 3D structure. Source: alphafold

Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3)

Receptor for inositol 1,4,5-trisphosphate, another messenger that mediates the release of intracellular calcium. .

Gene Information

Human
Gene Name:	ITPR3
Uniprot:	Q14573
Entrez:	3710

Family

Belongs to:

InsP3 receptor family

Alternative Names

FLJ36205; inositol 14,5-triphosphate receptor, type 3; inositol 14,5-trisphosphate receptor type 3; insP3R3; IP3 receptor isoform 3; IP3 receptor; IP3R 3; IP3R; IP3R3; Type 3 inositol 14,5-trisphosphate receptor; Type 3 InsP3 receptor

Molecular Weight

Mass (kDA):
304.106 kDA

Genomic Context


Human

Location:	6p21.31
Sequence:	6; NC_000006.12 (33621322..33696562)

Tissue Specificity

Expressed in intestinal crypt and villus epithelial cells.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Diabetes Mellitus
Diabetes Mellitus, Insulin-dependent
Lupus Erythematosus, Systemic
Rheumatoid Arthritis
Dysequilibrium Syndrome
Graves Disease
Autoimmune Diseases
Arthritis
Autoimmune Reaction
Aneurysm
Neoplasm Metastasis
Cardiac Arrhythmia
Metastatic Malignant Neoplasm To The Lymph Node

Metastatic Malignant Neoplasm To The Liver
Colonic Neoplasms
Malignant Tumor Of Colon
Carcinoma
Carcinogenesis
Mucocutaneous Lymph Node Syndrome
Malignant Neoplasms

Interacting Proteins

BAP1
TRPC3

Pathways

Localization
Secretion
Cell Proliferation
Insulin Secretion
Dna Repair
Rna Splicing
Cell Division
Tissue Development
Hair Cycle
Phagocytosis

Anagen
Telogen
Rna Processing
Pathogenesis

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITPR3

References

PMID: 8081734 by Yamamoto-Hino M., et al. Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

PMID: 8288584 by Maranto A.R.; Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium.