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IVNS1ABP Antibodies
AND IVNS1ABP ELISA kits, IVNS1ABP Proteins
Many biological assays use antibodies to detect IVNS1ABP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IVNS1ABP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IVNS1ABP antibodies...
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IVNS1ABP Infographic by Boster Bio
All IVNS1ABP Products
Product
Figures
Specificity
Applications
Price
$1062
Cat # PROTQ9Y6Y0
20 µg
Cat # PROTQ9Y6Y0
20 µg
Human
$628
Cat # LS010625
20 µg, 100 µg
Cat # LS010625
20 µg, 100 µg
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A10942-2
100 μg/vial
Cat # A10942-2
100 μg/vial
IVNS1ABP Overview
Facts about Influenza virus NS1A-binding protein.
Influenza virus NS1A-binding protein (IVNS1ABP)
Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (By similarity).
Protects cells from cell death induced by actin destabilization (By similarity). Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway raising the concentration of AHR accessible to activate transcription (PubMed:16582008).
Gene Information
| Human | |
|---|---|
| Gene Name: | IVNS1ABP |
| Uniprot: | Q9Y6Y0 |
| Entrez: | 10625 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
ARA3; aryl hydrocarbon receptor-associated 3; Aryl hydrocarbon receptor-associated protein 3; DKFZp686K06216; FLARA3; FLJ10962; FLJ35593; FLJ36593; HSPC068; influenza virus NS1A binding protein; influenza virus NS1A-binding protein; KIAA0850FLJ10069; KLHL39; NCX downstream gene 1; ND1; NS1; NS-1; NS1-binding protein; NS1BP; NS1-BPFLJ10411
Molecular Weight
Mass (kDA):
71.729 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q25.3 |
| Sequence: | 1; NC_000001.11 (185292367..185317292, complement) |
Subcellular Localizations
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus, nucleoplasm. Associated with actin filaments (By similarity). Localization related to speckle domains which correspond to interchromatin granules and are enriched in factors involved in pre-mRNA splicing (PubMed:9696811). Following influenza A virus infection, redistribution from speckles to a more diffuse distribution in the nucleoplasm (PubMed:9696811).
Diseases
- Influenza
- Orthomyxoviridae Infections
- Infective Disorder
- Virus Diseases
- Multiple Myeloma
- Inflammation
- Allergy
- Chimera Disorder
Pathways
- Cell Proliferation
- Cellular Localization
- Localization
- Conjugation
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IVNS1ABP
bosterbio.com/bosterbio-gene-info-cards/IVNS1ABP
References
PMID: 9696811 by Wolff T., et al. NS1-Binding protein (NS1-BP): a novel human protein that interacts with the influenza A virus nonstructural NS1 protein is relocalized in the nuclei of infected cells.
PMID: 16582008 by Dunham E.E., et al. The aryl hydrocarbon receptor signaling pathway is modified through interactions with a Kelch protein.