This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
KCNC1 / Voltage-gated potassium channel KCNC1 · IHC design guide
Design Immunohistochemistry for KCNC1
Plan chromogenic KCNC1 IHC in paraffin sections using cerebellar synaptic glomeruli as a high-staining reference (HPA tissue IHC). Compare adipose tissue adipocytes, where staining was not detected, and optimize catalog antibody A06871-1 within 1:100–1:300 (HPA tissue IHC; datasheet: A06871-1).
Evidence assembled Oct 2026 · For research use; verify linked source records and product datasheet before use
KCNC1 Immunohistochemistry Experimental Design Guide
Expected localisation, validated protocols, controls and antibodies — the at-a-glance facts below, then the full design guide.
Must know before staining
| Expected localisation | CNS processes (HPA tissue IHC); axonal membrane (UniProt) | |
| Staining pattern | Cerebellar synaptic processes; cortical neuronal cytoplasm (HPA tissue IHC) | |
| Antigen retrieval | Citrate pH 6.0 HIER, 95–98 °C, 20 min (rule: cytoplasmic / membrane antigen) | |
| Positive control | Cerebellum+2 more · see all | |
| Negative control | Adipose tissue+4 more · see all |
Important caveats
Reasons your staining may differ from the expected pattern.
| Fixation | Keep fixation consistent across sections (standard IHC practice; not target-specific). Selected-image fixative and duration unreported (datasheet A06871-1); verify before use. | |
| Caveat | Staining varies by region: high in cerebellum, low in caudate (HPA tissue IHC) | |
| Regulation | Brain-enriched RNA; regulation unreported (HPA tissue RNA) | |
| Isoform / epitope | 2 isoforms; confirm whether the epitope is extracellular or cytoplasmic (UniProt) |
Section 1
Recommended KCNC1 IHC & IF Protocols
The catalog antibody’s IHC-P protocol is accompanied by a published KCNC1 protocol for human seminoma and adjacent tissue (PMC8020201).
| Sample | Paraffin-embedded human brain tissue; fixative not specified (datasheet A06871-1) |
| Fixation | Image fixative and duration unreported (datasheet A06871-1); verify before use. |
| Sectioning | 4–5 µm sections on charged slides (standard) |
| Deparaffinisation | Xylene, graded ethanol series to water (standard) |
| Antigen retrieval | Heat-induced epitope retrieval in citrate buffer, pH 6.0, 20 min at 95–98 °C (standard rule: cytoplasmic / membrane antigen) |
| Peroxidase block | 3% H2O2, 10 min, room temperature (standard) |
| Blocking | 10% normal serum of the secondary host, 30 min, room temperature (standard) |
| Primary antibody | Rabbit anti-KCNC1, 1:100-1:300 (datasheet A06871-1) |
| Primary incubation | Overnight at 4 °C (standard) |
| Detection | HRP-polymer secondary, DAB chromogen 5–10 min (standard) |
| Counterstain | Hematoxylin, blue, dehydrate and mount (standard) |
| Expected result | KCNC1-positive staining in synaptic glomeruli - core of cerebellum (HPA tissue IHC: High). HPA tissue profile: Expression in processes in CNS and retina, most abundant in cerebellum granular layer. Additional cytoplasmic expression in neuronal cells of cerebral cortex and caudate. No signal in the no-primary control. |
💡Decision noteTry citrate pH 6.0 heat retrieval at 95–98 °C for 20 min first, given KCNC1’s membrane localization (page antigen retrieval; UniProt P48547).
Section 2
What Is the Expected KCNC1 Staining Pattern?
In paraffin-section IHC, expect KCNC1 staining in neuronal processes, strongest in cerebellar synaptic glomeruli, with weaker staining in cortical neurons and retinal processes (HPA: Enhanced tissue IHC; High in cerebellar synaptic glomeruli; Medium in cerebral cortical neurons and retinal inner plexiform layer). A process-associated pattern fits its cell, axonal and presynaptic membrane localization and six transmembrane segments (UniProt P48547: subcellular location and topology).
| Strong staining in cerebellar granular-layer synaptic glomeruli, especially their cores, with a process-rich pattern. | This is the clearest positive reference: HPA reports High staining in synaptic glomeruli and describes processes as the principal tissue pattern (HPA: cerebellum; Enhanced tissue IHC). Score the localized pattern as well as intensity; a uniformly stained section does not reproduce that distribution (HPA: tissue IHC). |
| Medium staining in cerebral cortical neuronal cells or the retinal inner plexiform layer; weak neuronal staining in caudate. | These sites provide secondary comparisons, with tissue-dependent intensity (HPA: Medium in cortex and retina; Low in caudate). HPA also describes cytoplasmic staining in cortical and caudate neurons, so cytoplasmic neuronal signal alone does not contradict its tissue observations (HPA: tissue IHC profile). |
| Predominantly nuclear staining in paraffin sections, without the expected neuronal-process pattern. | Treat this as a compartment mismatch and investigate artefact or nonspecific staining against the tissue IHC reference (HPA: tissue IHC profile; UniProt P48547: membrane localization). Nuclear locations are reported separately by HPA ICC-IF; that observation does not establish a predominantly nuclear paraffin-IHC pattern (HPA: ICC-IF subcellular summary). |
| Prominent staining of adipocytes or other cells reported as undetected, especially when it matches the surrounding background. | Consider cross-reactivity or endogenous detection activity before calling the signal KCNC1 (HPA: adipose adipocytes Not detected; adrenal glandular cells Not detected). Such staining is less persuasive than the documented neuronal-process pattern; evaluate the same cell type against its HPA tissue entry (HPA: tissue IHC). |
| Diffuse color throughout tissue, or no signal in cerebellar synaptic glomeruli. | Diffuse color obscures the expected process pattern; absent glomerular signal makes the run uninterpretable as a positive KCNC1 result (HPA: High in cerebellar synaptic glomeruli). Assess detection controls, background and tissue preservation using general IHC practice before drawing a biological conclusion. |
💡Expected KCNC1 appearanceCall a positive result when cerebellar synaptic glomerular cores show strong, localized process-associated staining, with potentially weaker cortical neuronal or retinal inner-plexiform staining; widespread uniform color or dominant nuclear-only IHC signal warrants investigation (HPA: High in cerebellum, Medium in cortex and retina; HPA: tissue IHC profile; UniProt P48547: membrane localization).
| Reference tissue and cell type (HPA: tissue IHC) | Cerebellar synaptic glomeruli offer the strongest supplied positive reference; cortical neurons and retinal inner plexiform layer are Medium, while caudate neurons are Low (HPA: tissue IHC). Compare like cell types and compartments when judging an apparently weak slide. |
| Antibody evidence (HPA: antibody validation; tissue IHC reliability) | HPA047634 has Enhanced IHC status, and the tissue profile has Enhanced reliability with RNA consistency and external characterization support (HPA: HPA047634 IHC; tissue IHC reliability). HPA048249 has no supplied IHC status; its Approved ICC status alone does not validate paraffin-section IHC (HPA: antibody validation). |
| Topology and epitope interpretation (UniProt P48547: topology) | KCNC1 has six transmembrane segments and annotated cytoplasmic regions, consistent with membrane-associated staining (UniProt P48547: topology and subcellular location). The supplied record does not locate either antibody's epitope; do not infer an antibody-specific retrieval or permeabilisation requirement from topology alone. |
| Molecular forms (UniProt P48547: isoforms, processing and modifications) | UniProt lists two isoforms, one chain spanning residues 1–511, two glycosylation sites and several phosphorylation sites (UniProt P48547: isoforms, chain and modified sites). Their effect on staining with the supplied antibodies is unreported; do not assign a distinct tissue pattern to an isoform or modification. |
| IF/ICC Q: Should its nuclear signal define the IHC result? | A: No. HPA ICC-IF reports approved nucleoplasm and nuclear-membrane locations, plus vesicles and cytosol (HPA: ICC-IF subcellular summary). Interpret that assay on its own terms; the paraffin-IHC tissue reference emphasizes CNS and retinal processes and neuronal cytoplasm (HPA: tissue IHC profile). |
| Fixation sensitivity | Target-specific fixation sensitivity is unreported in the supplied HPA and UniProt records. Record fixation conditions for comparisons as general IHC practice, without attributing any change in KCNC1 signal to fixation on this evidence. |
| Situation | Likely cause | Next action |
|---|---|---|
| No staining in cerebellar synaptic glomeruli (HPA: High). | A failed detection run, unsuitable antibody conditions or a section with poorly represented glomeruli could explain the absence (general IHC practice). | Check the positive-reference region, reagent controls and the catalog antibody's IHC-P instructions; repeat under controlled conditions before reporting absence (HPA: cerebellar glomeruli High; general IHC practice). |
| Only nuclei stain in neuronal tissue (HPA: tissue IHC profile). | The compartment differs from the process-rich tissue pattern (HPA: tissue IHC), although HPA ICC-IF separately reports nuclear locations (HPA: ICC-IF). | Compare with a cerebellar positive section and appropriate detection controls; report the assay-specific discrepancy rather than treating ICC-IF localization as paraffin-IHC validation (HPA: tissue IHC; ICC-IF; general IHC practice). |
| Adipocytes or adrenal glandular cells stain strongly (HPA: Not detected in those cells). | Cross-reactivity or endogenous detection activity is plausible when the reported negative cell types stain (HPA: tissue IHC; general IHC practice). | Inspect a no-primary control and address endogenous detection activity as appropriate for the detection chemistry; compare against the neuronal positive reference (HPA: cerebellar glomeruli High; general IHC practice). |
| Color is diffuse and the glomerular pattern is lost (HPA: cerebellar glomeruli High). | Excess background from antibody or detection conditions can obscure localized signal (general IHC practice). | Review blocking, antibody concentration, washing and detection time within the validated IHC workflow; judge improvement by restored localized contrast (HPA: tissue IHC profile; general IHC practice). |
| Cortex or retina looks weaker than cerebellum (HPA: tissue IHC). | That intensity ordering may reflect the supplied reference levels: cerebellar glomeruli High, cortical neurons and retinal inner plexiform layer Medium (HPA: tissue IHC). | Score each site against its own cell and layer reference; investigate a technical failure only if the known-positive pattern or run controls also fail (HPA: tissue IHC; general IHC practice). |
| A candidate antibody yields a different paraffin-IHC pattern from the reference (HPA: tissue IHC). | ICC approval alone does not establish its IHC performance; HPA048249 has Approved ICC status but no supplied IHC status (HPA: antibody validation). | Check the antibody's IHC validation and compare staining with the Enhanced IHC reference for HPA047634, using matched tissue and controls (HPA: antibody validation; general IHC practice). |
Experiment evidence
IHC & IF images showing KCNC1 staining
A06871-1 · IHCImmunohistochemistryt analysis of paraffin-embedded human brain, using KCNC1 Antibody. The lane on the right is blocked with the KCNC1 pepti
HPA · Cerebral cortexHuman Protein Atlas IHC, Cerebral cortex. Source: https://www.proteinatlas.org/ENSG00000129159-KCNC1/tissue/cerebral+cortex#imid_13667363
HPA · CerebellumHuman Protein Atlas IHC, Cerebellum. Source: https://www.proteinatlas.org/ENSG00000129159-KCNC1/tissue/cerebellum#imid_13667366
HPA · ColonHuman Protein Atlas IHC, Colon. Source: https://www.proteinatlas.org/ENSG00000129159-KCNC1/tissue/colon#imid_13759978
HPA · LiverHuman Protein Atlas IHC, Liver. Source: https://www.proteinatlas.org/ENSG00000129159-KCNC1/tissue/liver#imid_13759891
HPA · ICC-IF Rh30Human Protein Atlas immunofluorescence, Rh30, antibody HPA047634; green = KCNC1, blue = nucleus, red = microtubules.
HPA · ICC-IF Rh30Human Protein Atlas immunofluorescence, Rh30, antibody HPA047634; green = KCNC1, blue = nucleus, red = microtubules.
← swipe / scroll for more images →
Real IHC / IF data behind the staining-pattern expectations in this section.
Sample controls for KCNC1 IHC & IF
🧪Run cerebellum first and score staining in the synaptic glomeruli core, where KCNC1 is High (HPA: cerebellum, synaptic glomeruli core, High). Use adrenal gland glandular cells as a negative tissue (HPA: adrenal gland, glandular cells, Not detected); on the cerebellum slide, adjacent tissue outside the synaptic glomeruli core should provide a local background comparison, without assuming every surrounding cell is KCNC1-negative (HPA: cerebellum, synaptic glomeruli core, High).
Positive control tissue: Cerebellum (Synaptic glomeruli - core, HPA High)
Negative control tissue: Adipose tissue (HPA Not detected)
ICC-IF cell lines (HPA subcellular resource): HPA ICC-IF images show KCNC1 in Rh30, SH-SY5Y, U2OS, with annotated localisation: Nucleoplasm (approved), Nuclear membrane (approved) (HPA subcellular).
Technical controls: Include a no-primary, secondary-only control, a concentration-matched isotype control appropriate to the primary antibody’s host species and clonality, and a KCNC1 peptide-block control where the immunizing peptide is available (standard IHC practice; selected SKU A06871-1 caption: peptide block). For chromogenic cerebellum IHC, quench endogenous peroxidase before detection; assess endogenous biotin if using a biotin-based detection system (standard IHC practice).
⚠️Feasibility: A KCNC1-specific fixation window and fixation effect are unreported, and the fixative is unreported in the selected SKU’s paraffin-section brain caption (selected SKU A06871-1 caption). Antigen retrieval requirements must be determined empirically for this antibody; the supplied evidence does not establish whether frozen sections or IF are easier than paraffin IHC (selected SKU A06871-1 caption: paraffin-embedded brain). In brain IF, check for tissue autofluorescence when interpreting signal (standard IF practice).
HPA tissue IHC evidence for KCNC1
Comprehensive Human Protein Atlas IHC scoring per tissue (reliability: Enhanced — High consistency between antibody staining and RNA expression data. External characterization data supports antibody staining.). Rows are taken directly from the HPA tissue chart — click any row's HPA link to view the source.
Positive expression · recommended positive controls
| Tissue | Cell type | Level | Evidence | Source |
|---|---|---|---|---|
| Cerebellum | Synaptic glomeruli - core | High | Protein (IHC) | HPA → |
| Cerebral cortex | Neuronal cells | Medium | Protein (IHC) | HPA → |
| Retina | Inner plexiform layer | Medium | Protein (IHC) | HPA → |
Undetected expression · recommended negative controls
| Tissue | Cell type | Level | Evidence | Source |
|---|---|---|---|---|
| Adipose tissue | Adipocytes | Not detected | Protein (IHC) | HPA → |
| Adrenal gland | Glandular cells | Not detected | Protein (IHC) | HPA → |
| Appendix | Endocrine cells | Not detected | Protein (IHC) | HPA → |
| Bone marrow | Hematopoietic cells | Not detected | Protein (IHC) | HPA → |
| Breast | Adipocytes | Not detected | Protein (IHC) | HPA → |
Section 3
Advanced KCNC1 IHC Tips
Troubleshoot KCNC1 staining in paraffin sections by checking retrieval, controls, compartment, and scoring against the reported brain tissue pattern.
How should I retrieve KCNC1 when brain staining is weak?
Use citrate pH 6.0 heat-induced epitope retrieval at 95–98 °C for 20 min on paraffin sections (page retrieval setting). The selected A06871-1 image shows paraffin-embedded human brain, but its caption gives neither a retrieval recipe nor the fixative (caption: A06871-1). Keep section preparation, antibody incubation, and chromogenic development matched while comparing retrieval runs (standard IHC practice). Judge improvement in the cerebellar synaptic glomeruli core and neuronal processes, rather than by a general rise in brown staining (HPA tissue IHC). If signal remains weak, check antibody dilution and the integrity of the positive-control section before changing the retrieval condition (standard IHC practice).
Could fixation explain inconsistent KCNC1 staining between paraffin blocks?
Target-specific fixation sensitivity is unknown: the selected paraffin brain caption does not identify its fixative, and the supplied evidence provides no KCNC1 fixation comparison (caption: A06871-1). Record the fixative and fixation duration for every block, then compare sections processed and retrieved together (standard IHC practice). If preparing new material, 10% neutral buffered formalin is a conventional paraffin IHC starting condition, not a KCNC1-validated requirement (standard IHC practice). Include the same positive-control brain section in each run so that a change in staining can be assessed alongside processing differences (HPA tissue IHC; standard IHC practice). Do not assign a fixation effect to KCNC1 from its membrane topology or phosphorylation sites alone (UniProt P48547 topology and modified residues).
Which staining compartments are plausible for KCNC1 in brain sections?
Prioritize staining in neuronal processes and synaptic regions: tissue IHC reports strong cerebellar synaptic glomeruli core staining and additional neuronal cytoplasmic expression (HPA tissue IHC). KCNC1 is annotated at the cell membrane, axon, and presynaptic membrane, including perisynaptic and extrasynaptic membranes (UniProt P48547 subcellular location). A fine process-associated pattern can therefore be more informative than scoring neuronal cell bodies alone (HPA tissue IHC; UniProt P48547 subcellular location). Nuclear staining needs separate scrutiny because HPA reports nucleoplasm and nuclear membrane localization in its subcellular imaging data (HPA subcellular). Compare the compartment pattern with matched controls and tissue anatomy before assigning nuclear chromogen to a specific KCNC1 pool (standard IHC practice).
How can an unknown antibody epitope affect KCNC1 IHC interpretation?
KCNC1 has 2 annotated isoforms, but the supplied antibody caption does not map the recognized epitope or establish isoform selectivity (UniProt P48547 isoforms; caption: A06871-1). The canonical protein has 6 transmembrane segments and cytoplasmic regions at residues 1–190 and 437–511 (UniProt P48547 topology). Obtain the immunogen coordinates before interpreting a negative compartment or comparing results across antibodies (standard IHC practice). Glycosylation sites at residues 220 and 229 and reported phosphoserines identify possible molecular context, but no supplied evidence shows that either modification changes this antibody’s IHC signal (UniProt P48547 glycosylation and modified residues). Report staining as KCNC1 immunoreactivity unless epitope mapping and appropriate controls support a narrower isoform claim (standard IHC practice).
How should I plan IF to examine the KCNC1 pattern seen by IHC?
Treat IF as a separate assay and multiplex KCNC1 with a neuronal marker to identify the expected cell population in brain tissue (HPA tissue IHC; standard IF practice). Add a synaptic or process marker when the question concerns cerebellar glomeruli or axonal staining (HPA tissue IHC; UniProt P48547 subcellular location). Choose spectrally separated fluorophores and evaluate a far-red channel against tissue autofluorescence using unstained controls (standard IF practice). Set permeabilisation according to the mapped epitope: cytoplasmic termini require intracellular access, whereas an accessible extracellular epitope may not (UniProt P48547 topology; standard IF practice). The supplied paraffin IHC caption does not establish an IF fixation, dilution, or permeabilisation condition for A06871-1 (caption: A06871-1).
What controls help separate KCNC1 signal from chromogenic background?
Run a no-primary control to reveal detection-reagent background and assess endogenous peroxidase blocking before DAB development (standard chromogenic IHC practice). For a conventional peroxidase workflow, 3% hydrogen peroxide for about 10 min is a general starting condition to check against tissue compatibility, not KCNC1-specific evidence (standard IHC practice). Titrate the primary antibody and keep DAB development comparable across sections before attributing diffuse brown staining to KCNC1 (standard IHC practice). The selected brain image includes a KCNC1 peptide-blocked comparison, which is useful for assessing antibody-dependent staining in that image (caption: A06871-1). Interpret that comparison alongside anatomical pattern and no-primary controls, since peptide competition alone cannot establish every stained cell or compartment (standard IHC practice).
How should I quantify KCNC1 across brain sections? ⚠ ANSWER MARKED FOR VERIFICATION
Define the anatomical region and staining compartment before scoring because KCNC1 tissue IHC is strongest in the cerebellar synaptic glomeruli core and also appears in neuronal processes (HPA tissue IHC). For neuronal cell bodies, record the percentage of positive cells and an intensity-weighted H-score on a 0–300 scale (standard IHC practice). For process-rich regions, measure positive area or signal density per mm² of viable, annotated tissue instead of forcing a cell-count denominator (standard image-analysis practice). Normalize comparisons to the same region, viable area, section handling, and chromogenic development settings (standard IHC practice). Set thresholds with matched negative controls and apply them consistently across batches (standard IHC practice).
When is KCNC1 staining convincing, and when might it be artefact?
A convincing tissue pattern follows neuronal processes or synaptic regions, including the reported high signal in cerebellar synaptic glomeruli core (HPA tissue IHC; UniProt P48547 subcellular location). Check unexpected staining in other cell types against the same section’s anatomy and controls rather than assuming it reflects KCNC1 (standard IHC practice). Edge-restricted staining, necrotic areas, and signal reproduced in a no-primary control suggest processing or detection artefact (standard IHC practice). Residual endogenous peroxidase can also produce misleading DAB signal, so review the peroxidase-block control when staining is diffuse (standard chromogenic IHC practice). Nuclear signal warrants careful review because HPA subcellular imaging reports nuclear locations, while the supplied tissue IHC pattern emphasizes processes (HPA subcellular; HPA tissue IHC).
Boster reagents
Best KCNC1 / Voltage-gated potassium channel KCNC1 IHC Antibodies
The catalog lists KCNC1 antibodies for IHC and IF in human, mouse, and rat (catalog: applications and reactivity); the supplied figure shows paraffin-embedded human brain IHC only (A06871-1 image caption).
Real IHC data
Anti-KV3.1 KCNC1 Antibody
Cat # A06871-1
A06871-1 lists IHC and IF for human, mouse, and rat, with an IHC figure captioned as paraffin-embedded human brain (catalog: applications, reactivity, image caption). A06871-2 lists IHC, IF, and ICC for human, mouse, and rat; no image caption is supplied (catalog: applications, reactivity, image alts).
Which to pick: For tissue IHC, choose A06871-1 when a paraffin-section example matters: its own caption shows human brain, but reports no fixative (A06871-1 image caption). For IF/ICC, choose A06871-2 because both applications are listed; A06871-1 lists IF but not ICC (catalog: applications). Both list human, mouse, and rat reactivity for cross-species planning; both have rabbit hosts, and neither has a reported clone (catalog: reactivity, host, clone).
Each figure is that product's own IHC / IF validation image from its datasheet.
References
- UniProt Consortium. UniProt entry P48547 (KCNC1_HUMAN, Voltage-gated potassium channel KCNC1).
- Human Protein Atlas. KCNC1 tissue IHC expression (reliability: Enhanced).
- Human Protein Atlas. KCNC1 subcellular location (ICC-IF): Mainly localized to the nucleoplasm and nuclear membrane. In addition localized to vesicles and cytosol..
- Human Protein Atlas. KCNC1 antibody validation summary (2 antibodies).
- Methylation gene KCNC1 is associated with overall survival in patients with seminoma. Oncology reports 2021 — PMC8020201.
- PubMed PMID:8449507 — UniProt-cited evidence.
- PubMed PMID:16554811 — UniProt-cited evidence.
- PubMed PMID:15489334 — UniProt-cited evidence.
Immunohistochemistry protocol sheet for KCNC1 (Voltage-gated potassium channel KCNC1). Expected localisation CNS processes (HPA tissue IHC); axonal membrane (UniProt). Antigen retrieval: Citrate pH 6.0 HIER, 95–98 °C, 20 min (rule: cytoplasmic / membrane antigen). Validated IHC antibody: A06871-1 at 1:100-1:300 (the product's own IHC validation image is shown). Controls (HPA): positive Cerebellum (Synaptic glomeruli - core); negative Adipose tissue. IHC workflow; specimen preparation unspecified. Protocol steps: 1. Sample: Paraffin-embedded human brain tissue; fixative not specified (datasheet A06871-1); 2. Fixation: Image fixative and duration unreported (datasheet A06871-1); verify before use.; 3. Sectioning: 4–5 µm sections on charged slides (standard); 4. Deparaffinisation: Xylene, graded ethanol series to water (standard); 5. Antigen retrieval: Heat-induced epitope retrieval in citrate buffer, pH 6.0 , 20 min at 95–98 °C…; 6. Peroxidase block: 3% H2O2, 10 min , room temperature (standard); 7. Blocking: 10% normal serum of the secondary host, 30 min , room temperature (standard); 8. Primary antibody: Rabbit anti-KCNC1, 1:100-1:300 (datasheet A06871-1); 9. Primary incubation: Overnight at 4 °C (standard). Watch for: Fixation: Keep fixation consistent across sections (standard IHC practice; not target-specific). Selected-image fixative and duration unreported (datasheet A06871-1); verify before use.; Caveat: Staining varies by region: high in cerebellum, low in caudate (HPA tissue IHC); Isoform / epitope: 2 isoforms; confirm whether the epitope is extracellular or cytoplasmic (UniProt); Regulation: Brain-enriched RNA; regulation unreported (HPA tissue RNA). Evidence: UniProt P48547, HPA tissue IHC · Enhanced, HPA ICC-IF · Mainly localized to the nucleoplasm and nuclear membrane. In…, Datasheet A06871-1, PMC8020201. QR code links to https://www.bosterbio.com/bosterbio-gene-info-cards/KCNC1/immunohistochemistry-ihc-guide.