KCNV1 Antibodies

AND KCNV1 ELISA kits, KCNV1 Proteins

Many biological assays use antibodies to detect KCNV1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNV1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNV1 antibodies...

We validate the specificity of these antibodies to KCNV1 by testing them on tissues known to express KCNV1 positively and negatively. Browse below to find the KCNV1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KCNV1 Infographic by Boster Bio

All KCNV1 Products

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KCNV1 (NM_014379) Human Over-expression Lysate

Human

$628
Cat # LS027012
20 µg, 100 µg

KCNV1 Overview

Facts about Potassium voltage-gated channel subfamily V member 1.

KCNV1 3D structure. Source: alphafold

Potassium voltage-gated channel subfamily V member 1 (KCNV1)

Potassium channel subunit that doesn't form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation.

Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, maybe by trapping them in intracellular membranes. .

Gene Information

Human
Gene Name:	KCNV1
Uniprot:	Q6PIU1
Entrez:	27012

Family

Belongs to:

potassium channel family

Alternative Names

HNKA; KCNB3; KV2.3; KV8.1; Neuronal potassium channel alpha subunit HNKA; potassium channel Kv8.1; potassium channel, subfamily V, member 1; potassium voltage-gated channel subfamily V member 1; Voltage-gated potassium channel subunit Kv8.1

Molecular Weight

Mass (kDA):
56.304 kDA

Genomic Context


Human

Location:	8q23.2
Sequence:	8; NC_000008.11 (109963636..109975771, complement)

Tissue Specificity

Detected in brain.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2.

Diseases

Bladder Neoplasm
Neoplasm Recurrence, Local
Malignant Neoplasm Of Urinary Bladder
Epilepsy
Neuralgia
Epilepsies, Myoclonic
Malignant Neoplasms
Acute Onset Pain
Nervousness

Pain
Inflammation
Metabolic Bone Disorder

Pathways

Methylation
Dna Methylation

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNV1

References

PMID: 8670833 by Hugnot J.-P., et al. Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels.

PMID: 12383276 by Sano A., et al. Positional candidate approach for the gene responsible for benign adult familial myoclonic epilepsy.