ER lumen protein-retaining receptor 1 (KDELR1)

Required for the retention of luminal endoplasmic reticulum resident proteins through vesicular recycling. This receptor recognizes the C-terminal K-D-E-L motif.

COPI-coated transport intermediates, either in the form of round vesicles or as tubular procedures, mediate retrograde visitors of the KDEL receptor-ligand complexes. Also required for normal vesicular traffic through the Golgi.