SF3A3 Antibodies

AND SF3A3 ELISA kits, SF3A3 Proteins

Many biological assays use antibodies to detect SF3A3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SF3A3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SF3A3 antibodies...

We validate the specificity of these antibodies to SF3A3 by testing them on tissues known to express SF3A3 positively and negatively. Browse below to find the SF3A3 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SF3A3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SF3A3 IHC Guide

SF3A3 Infographic by Boster Bio

All SF3A3 Products

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Product

Figures

Specificity

Applications

Price

Anti-SF3A3 Antibody Picoband®

Western blot analysis of SF3A3 using anti-SF3A3 antibody (A10671-1)

IHC analysis of SF3A3 using anti-SF3A3 antibody (A10671-1)

+12

Human, Mouse, Rat

ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # A10671-1
100 μg/vial

Anti-Zebrafish SF3A3 Antibody Picoband®

Western blot analysis of SF3A3 using anti-SF3A3 antibody (AZQ6DRK2)

Zebrafish

$470
Cat # AZQ6DRK2
100 μg/vial

Anti-SF3A3 Rabbit Monoclonal Antibody

Western blot analysis of SF3A3 expression in A431 cell lysate

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M10671
100 μl/vial

SF3A3 (NM_006802) Human Over-expression Lysate

Human

$628
Cat # LS010946
20 µg, 100 µg

SF3A3 (NM_006802) Human Recombinant Protein

Coomassie blue staining of purified SF3A3 protein

$1249
Cat # PROTQ12874
20 µg

SF3A3 Overview

Facts about Splicing factor 3A subunit 3.

SF3A3 3D structure. Source: alphafold

Splicing factor 3A subunit 3 (SF3A3)

Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.

May also be involved in the assembly of the 'E' complex. .

Gene Information

Human
Gene Name:	SF3A3
Uniprot:	Q12874
Entrez:	10946

Family

Belongs to:

SF3A3 family

Alternative Names

PRP9; PRPF9; SAP 61; SAP61splicing factor 3a, subunit 3, 60kD; SF3a60pre-mRNA splicing factor SF3a (60kD); spliceosome associated protein 61; Spliceosome-associated protein 61; splicing factor 3A subunit 3; splicing factor 3a, subunit 3, 60kDa

Molecular Weight

Mass (kDA):
58.849 kDA

Genomic Context


Human

Location:	1p34.3
Sequence:	1; NC_000001.11 (37956975..37990022, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus speckle. Nucleus.

Diseases

Heat Stress Disorders
Persistent Superficial Gastritis
Gastritis

Interacting Proteins

HSPB1
SF3A1
TADA2A
TRIM69
ZNF212

Pathways

Transport
Dna Replication
Oxidative Phosphorylation
Pathogenesis

PTMs

Sumoylation

Phosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SF3A3

References

PMID: 8022796 by Chiara M.D., et al. Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114.

PMID: 7816610 by Kraemer A., et al. Splicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivo.