KCNV2 Antibodies

AND KCNV2 ELISA kits, KCNV2 Proteins

Many biological assays use antibodies to detect KCNV2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNV2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNV2 antibodies...

We validate the specificity of these antibodies to KCNV2 by testing them on tissues known to express KCNV2 positively and negatively. Browse below to find the KCNV2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KCNV2 Infographic by Boster Bio

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Anti-KV8.2 KCNV2 Antibody

7 Q&As

Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung

Western Blot analysis of MCF-7 cells using KV8

Western blot analysis of lysates from MCF-7 cells, using KCNV2 Antibody

Human, Mouse

IHC, WB

$399
Cat # A08497
100μl

KCNV2 Overview

Facts about Potassium voltage-gated channel subfamily V member 2.

KCNV2 3D structure. Source: alphafold

Potassium voltage-gated channel subfamily V member 2 (KCNV2)

Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.

Gene Information

Human
Gene Name:	KCNV2
Uniprot:	Q8TDN2
Entrez:	169522

Family

Belongs to:

potassium channel family

Alternative Names

KV11.1; Kv8.2; MGC120515; potassium channel, subfamily V, member 2; potassium voltage-gated channel subfamily V member 2; RCD3B; voltage-gated potassium channel Kv8.2; Voltage-gated potassium channel subunit Kv8.2

Molecular Weight

Mass (kDA):
62.459 kDA

Genomic Context


Human

Location:	9p24.2
Sequence:	9; NC_000009.12 (2717510..2730037)

Tissue Specificity

Detected in lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary and colon.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1.

Diseases

Dystrophy
Retinal Diseases
Retinitis Pigmentosa
Retinal Dystrophies
Long Qt Syndrome
Color Vision Defect
Retinal Degeneration
Photophobia
Atrophy
Nystagmus
Sudden Death
Channelopathies

Epilepsy
Cardiac Arrhythmia
Tachycardia, Ventricular
Visual Impairment
Amaurosis
Ventricular Tachycardia, Catecholaminergic Polymorphic, 1 (disorder)
Strabismus

Pathways

Swimming
Phototransduction
Pathogenesis
Localization
Protein Processing

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNV2

References

PMID: 12060745 by Ottschytsch N., et al. Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.

PMID: 16909397 by Wu H., et al. Mutations in the gene KCNV2 encoding a voltage-gated potassium channel subunit cause 'cone dystrophy with supernormal rod electroretinogram' in humans.