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- Table of Contents
Facts about Lymphocyte cytosolic protein 2.
| Human | |
|---|---|
| Gene Name: | LCP2 |
| Uniprot: | Q13094 |
| Entrez: | 3937 |

| Belongs to: |
|---|
| No superfamily |

LCP2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of76kD); lymphocyte cytosolic protein 2; SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP-76 tyrosine phosphoprotein; SLP76; SLP-76; SLP7676 kDa tyrosine phosphoprotein
Mass (kDA):
60.188 kDA

| Human | |
|---|---|
| Location: | 5q35.1 |
| Sequence: | 5; NC_000005.10 (170246233..170297777, complement) |
Highly expressed in spleen, thymus and peripheral blood leukocytes. Highly expressed also in T-cell and monocytic cell lines, expressed at lower level in B-cell lines. Not detected in fibroblast or neuroblastoma cell lines.
Cytoplasm.





PMID: 7706237 by Jackman J.K., et al. Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells.
PMID: 11301322 by Moog-Lutz C., et al. PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells.