LCP2 Antibodies

AND LCP2 ELISA kits, LCP2 Proteins

Many biological assays use antibodies to detect LCP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LCP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LCP2 antibodies...

We validate the specificity of these antibodies to LCP2 by testing them on tissues known to express LCP2 positively and negatively. Browse below to find the LCP2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for LCP2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the LCP2 IHC Guide

LCP2 Infographic by Boster Bio

All LCP2 Products

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Product

Figures

Specificity

Applications

Price

Anti-SLP-76 (G122) LCP2 Antibody

Immunohistochemistry (IHC) analyzes of SLP-76 (G122) pAb in paraffin-embedded human breast carcinoma tissue at 1:100

Human, Mouse, Rat

IHC, WB

$405
Cat # A04880
100ul

SLP76 (LCP2) (NM_005565) Human Over-expression Lysate

Human

$628
Cat # LS003937
20 µg, 100 µg

Human SLP-76/LCP2 Recombinant Protein

SDS-PAGE

$350
Cat # PROTQ13094
Starting from 10ug

LCP2 Overview

Facts about Lymphocyte cytosolic protein 2.

LCP2 3D structure. Source: alphafold

Lymphocyte cytosolic protein 2 (LCP2)

Involved in T-cell antigen receptor mediated signaling. .

Gene Information

Human
Gene Name:	LCP2
Uniprot:	Q13094
Entrez:	3937

Family

Belongs to:

No superfamily

Alternative Names

LCP2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of76kD); lymphocyte cytosolic protein 2; SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP-76 tyrosine phosphoprotein; SLP76; SLP-76; SLP7676 kDa tyrosine phosphoprotein

Molecular Weight

Mass (kDA):
60.188 kDA

Genomic Context


Human

Location:	5q35.1
Sequence:	5; NC_000005.10 (170246233..170297777, complement)

Tissue Specificity

Highly expressed in spleen, thymus and peripheral blood leukocytes. Highly expressed also in T-cell and monocytic cell lines, expressed at lower level in B-cell lines. Not detected in fibroblast or neuroblastoma cell lines.

Subcellular Localizations

Cytoplasm.

Diseases

Tissue Adhesions
Arthritis
Leukemia
Rheumatoid Arthritis
Rectal Carcinoma
Fracture Of First Cervical Vertebra
Psoriasis
Milroy Disease
Multiple Malignancy
Glioblastoma
Leukemia L1210
Acute Lymphocytic Leukemia

Autoimmune Diseases
Lymphedema
Hypokinesia
Rheumatism
Malignant Neoplasms
Autoimmune Reaction
Neoplasms

Interacting Proteins

CD6
EGFR
FXR2
FYB1
GOLGA2

GRAP2
Grap2
GRB2
ITK
MAP4K3

Map4k3
NCK1
NCK2
PLCG1
STAM

STAM2
VAV1

Pathways

Dosage Compensation
Pathogenesis
Cell Adhesion
Transposition
Mitosis
Dna Methylation
Regulation Of Seed Development
Localization
Methylation
Seed Development

Reverse Transcription
Cell Cycle
Secretion
Cell-cell Adhesion

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LCP2

References

PMID: 7706237 by Jackman J.K., et al. Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells.

PMID: 11301322 by Moog-Lutz C., et al. PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells.