Magi3 Antibodies

AND Magi3 ELISA kits, Magi3 Proteins

Many biological assays use antibodies to detect Magi3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Magi3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Magi3 antibodies...

We validate the specificity of these antibodies to Magi3 by testing them on tissues known to express Magi3 positively and negatively. Browse below to find the Magi3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Magi3 Infographic by Boster Bio

All Magi3 Products

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MAGI3 (NM_152900) Human Recombinant Protein

Coomassie blue staining of purified MAGI3 protein

$1249
Cat # PROTQ5TCQ9
20 µg

MAGI3 (NM_152900) Human Over-expression Lysate

Human

$960
Cat # LS260425
20 µg, 100 µg

Anti-MAGI3 Antibody Picoband®

Western blot analysis of MAGI3 using anti-MAGI3 antibody (A06048)

Flow Cytometry analysis of 293T cells using anti-MAGI3 antibody (A06048)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A06048
100 μg/vial

Magi3 Overview

Facts about Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3.

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Magi3)

Acts as a scaffolding protein in cell-cell junctions, thereby regulating various cellular and signaling procedures. Cooperates with PTEN to modulate the kinase activity of AKT1.

Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may connect receptor tyrosine phosphatase with its substrates in the plasma membrane. In polarized epithelial cells, involved in effective trafficking of TGFA to the cell surface.

Gene Information

Mouse
Gene Name:	Magi3
Uniprot:	Q9EQJ9
Entrez:	99470

Family

Belongs to:

MAGUK family

Alternative Names

dJ730K3.2; MAGI-3; membrane associated guanylate kinase, WW and PDZ domain containing 3; membrane-associated guanylate kinase inverted 3; membrane-associated guanylate kinase-related 3; WW and PDZ domain-containing protein 3

Molecular Weight

Mass (kDA):
161.672 kDA

Genomic Context


Mouse

Location:	3 F2.2\|3 45.52 cM
Sequence:	3;

Tissue Specificity

Widely expressed. Colocalizes with TGFA in neurons in the cortex and dentate gyrus, as well as in ependymal cells and some astrocytes (at protein level). Present in lens epithelium.

Diseases

Malignant Neoplasms
Neoplasms
Tissue Adhesions
Cell Invasion
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Strabismus
Malignant Tumor Of Colon
Carcinogenesis
Mammary Neoplasms
Adenocarcinoma
Melanoma
Colonic Neoplasms

Glioblastoma
Malignant Paraganglionic Neoplasm
Neoplasm Invasiveness
Malignant Neoplasm Of Lung
Carcinoma
Arthritis
Adenomatous Polyposis Coli

Pathways

Neuron Migration
Mrna Splicing
Cell Migration
Cell Cycle
Cell Motility
Neurogenesis
Cell Growth

Segmentation
Localization

PTMs

Phosphorylation

Dephosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Magi3

References

PMID: 15652357 by Franklin J.L., et al. Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein.

PMID: 14645510 by Nguyen M.M., et al. Requirement of PDZ-containing proteins for cell cycle regulation and differentiation in the mouse lens epithelium.