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- Table of Contents
MAP2K3 Antibodies
AND MAP2K3 ELISA kits, MAP2K3 Proteins
Many biological assays use antibodies to detect MAP2K3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAP2K3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAP2K3 antibodies...
Designing a Western blot for MAP2K3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MAP2K3 Western Blot GuideMAP2K3 Infographic by Boster Bio
All MAP2K3 Products
Product
Figures
Specificity
Applications
Price
Anti-MEK3/MAP2K3 Antibody Picoband®
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9763
100 μg/vial
Cat # PB9763
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02916
100 μl
Cat # M02916
100 μl
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02916-1
100 μl
Cat # M02916-1
100 μl
Dog, Human, Monkey, Mouse, Rat
IF, IHC, WB
$523
Cat # M02916-2
100 µl
Cat # M02916-2
100 µl
Dog, Human, Monkey, Mouse, Rat
IF, IHC, WB
$523
Cat # M02916-3
100 µl
Cat # M02916-3
100 µl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M02916-5
20μL, 40μL, 100μL, 200μL
Cat # M02916-5
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A02916S218
100ul
Cat # A02916S218
100ul
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A02916T222
100ul
Cat # A02916T222
100ul
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$405
Cat # A02916-1
100ul
Cat # A02916-1
100ul
Human, Mouse, Rat
ELISA
$540
Cat # EKC2568
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2568
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2463
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2463
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1371
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1371
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$380
Cat # A02916T394
100ul
Cat # A02916T394
100ul
MAP2K3 Overview
Facts about Dual specificity mitogen-activated protein kinase kinase 3.
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3)
Dual specificity kinase. Is triggered by cytokines and environmental stress in vivo.
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14.
Gene Information
| Human | |
|---|---|
| Gene Name: | MAP2K3 |
| Uniprot: | P46734 |
| Entrez: | 5606 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
MAP kinase kinase 3; MAP2K3; MAPK/ERK kinase 3; MAPKK 3; MAPKK3PRKMK3dual specificity mitogen-activated protein kinase kinase 3; MEK3; MEK3MEK 3; mitogen activated protein kinase kinase 3; mitogen-activated protein kinase kinase 3; MKK3; MKK3EC 2.7.12.2; PRKMK3
Molecular Weight
Mass (kDA):
39.318 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p11.2 |
| Sequence: | 17; NC_000017.11 (21284679..21315240) |
Tissue Specificity
Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
Diseases
- Malignant Neoplasms
- Neoplasms
- Inflammation
- Carcinoma
- Tissue Adhesions
- Cell Transformation, Neoplastic
- Hypertrophy
- Fibrosis
- Anthrax Disease
- Arthritis
- Cell Invasion
- Malignant Neoplasm Of Breast
Interacting Proteins
- DYRK1B
- LRRK2
- MAP3K5
- MAPK14
- TINF2
Pathways
- Cell Death
- Cell Cycle
- Localization
- Cell Proliferation
- Cell Growth
- Secretion
- Immune Response
- Cytokine Production
- Pathogenesis
- Transport
- Inflammatory Response
- Angiogenesis
PTMs
- Phosphorylation
- Cleavage
- Dephosphorylation
- Reduction
Research Areas
- Angiogenesis
- Cancer
- Hypoxia
- Lipid and Metabolism
- Phospho-Specific
- Protein Kinase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAP2K3
bosterbio.com/bosterbio-gene-info-cards/MAP2K3
References
PMID: 7839144 by Derijard B., et al. Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms.
PMID: 8900184 by Moriguchi T., et al. Purification and identification of a major activator for p38 from osmotically shocked cells: activation of mitogen-activated protein kinase kinase 6 by osmotic shock, tumor necrosis factor-alpha, and H2O2.
2 Publications of Boster MAP2K3 Antibodies & ELISA Kits
- PubMed ID: 29410394, Cheng H, Wang W, Wang G, Wang A, Du L, Lou W. Med Sci Monit. 2018 Feb 7;24:768-7...
- PubMed ID: 24112539, Xu G, Zhang Y, Wei J, Jia W, Ge Z, Zhang Z, Liu X. Bmc Cancer. 2013 Oct 10;13:46...
*More publications can be found for each product on its corresponding product page