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- Table of Contents
MAP2K5 Antibodies
AND MAP2K5 ELISA kits, MAP2K5 Proteins
Many biological assays use antibodies to detect MAP2K5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAP2K5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAP2K5 antibodies...
Designing a Western blot for MAP2K5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MAP2K5 Western Blot GuideMAP2K5 Infographic by Boster Bio
All MAP2K5 Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03980-3
100 μg/vial
Cat # A03980-3
100 μg/vial
Human, Mouse, Rat
ELISA, IF, ICC, WB
$370
Cat # A03980-4
100 μg/vial
Cat # A03980-4
100 μg/vial
MAP2K5 Overview
Facts about Dual specificity mitogen-activated protein kinase kinase 5.
Dual specificity mitogen-activated protein kinase kinase 5 (MAP2K5)
Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway seems to play a vital role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.
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Gene Information
| Human | |
|---|---|
| Gene Name: | MAP2K5 |
| Uniprot: | Q13163 |
| Entrez: | 5607 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
HsT17454; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAP2K5; MAPK/ERK kinase 5; MAPKK 5; MAPKK5; MAPKK5EC 2.7.12.2; MEK5; MEK5MEK 5; mitogen-activated protein kinase kinase 5; MKK5; PRKMK5; PRKMK5dual specificity mitogen-activated protein kinase kinase 5
Molecular Weight
Mass (kDA):
50.112 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q23 |
| Sequence: | 15; NC_000015.10 (67542685..67807114) |
Tissue Specificity
Expressed in many adult tissues. Abundant in heart and skeletal muscle.
Diseases
- Malignant Neoplasms
- Neoplasms
- Restless Legs Syndrome
- Agitation
- Neoplasm Metastasis
- Obesity
- Hypertrophy
- Malignant Neoplasm Of Prostate
- Carcinogenesis
- Prostatic Neoplasms
- Cell Invasion
- Carcinoma
- Diabetes Mellitus
Interacting Proteins
- GRB2
- MAP3K3
- MAPK7
Pathways
- Localization
- Cell Proliferation
- Pathogenesis
- Chemotaxis
- Cell Cycle
- Mapk Cascade
- Cell Growth
- Angiogenesis
- Cell Cycle Arrest
- Cell Differentiation
- Dna Methylation
- Methylation
- Cell Death
PTMs
- Phosphorylation
- Methylation
Research Areas
- Neuroscience
- Protein Kinase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAP2K5
bosterbio.com/bosterbio-gene-info-cards/MAP2K5
References
PMID: 7759517 by Zhou G., et al. Components of a new human protein kinase signal transduction pathway.
PMID: 9384584 by Kato Y., et al. BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C.