MASP2 Antibodies

AND MASP2 ELISA kits, MASP2 Proteins

Many biological assays use antibodies to detect MASP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MASP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MASP2 antibodies...

We validate the specificity of these antibodies to MASP2 by testing them on tissues known to express MASP2 positively and negatively. Browse below to find the MASP2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for MASP2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the MASP2 Western Blot Guide

MASP2 Infographic by Boster Bio

All MASP2 Products

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Product

Figures

Specificity

Applications

Price

Anti-TRPS1 Antibody Picoband®

Western blot analysis of TRPS1 using anti-TRPS1 antibody (A02328-2)

IHC analysis of TRPS1 using anti-TRPS1 antibody (A02328-2)

IF analysis of TRPS1 using anti-TRPS1 antibody (A02328-2) and anti-Tubulin Alpha antibody (M03989-3)

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A02328-2
100 μg/vial

Anti-MASP2 Antibody Picoband®

Western blot analysis of MASP2 using anti-MASP2 antibody (A02323-1)

Flow Cytometry analysis of A431 cells using anti-MASP2 antibody (A02323-1)

Flow Cytometry analysis of HepG2 cells using anti-MASP2 antibody (A02323-1)

Human

Flow Cytometry, WB

$370
Cat # A02323-1
100 μg/vial

Anti-MASP2 Reference Antibody (narsoplimab)

The purity of Anti-MASP2 Reference Antibody (narsoplimab)is more than 98

Immobilized human MASP 2A His at 2 &mug/mL can bind Anti-MASP2 Reference Antibody (narsoplimab)

Human, Mouse, Rat

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M02323-1
100 μg

MASP2 (NM_139208) Human Over-expression Lysate

Human

$628
Cat # LS010747
20 µg, 100 µg

MASP2 Overview

Facts about Mannan-binding lectin serine protease 2.

MASP2 3D structure. Source: alphafold

Mannan-binding lectin serine protease 2 (MASP2)

Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, resulting in their activation and to the formation of C3 convertase.

Gene Information

Human
Gene Name:	MASP2
Uniprot:	O00187
Entrez:	10747

Family

Belongs to:

peptidase S1 family

Alternative Names

EC 3.4.21; EC 3.4.21.104; mannan-binding lectin serine peptidase 1 pseudogene 1; mannan-binding lectin serine peptidase 2; mannan-binding lectin serine protease 1 pseudogene 1; mannan-binding lectin serine protease 2; Mannose-binding protein-associated serine protease 2; MAP19; MASP1P1; MASP-2; MBL-associated plasma protein of 19 kD; MBL-associated serine protease 2; small MBL-associated protein; sMAP

Molecular Weight

Mass (kDA):
75.702 kDA

Genomic Context


Human

Location:	1p36.22
Sequence:	1; NC_000001.11 (11026523..11047239, complement)

Tissue Specificity

Plasma.

Subcellular Localizations

Secreted.

Diseases

Infective Disorder
Malignant Neoplasms
Pneumonia
Inflammation
Autoimmune Reaction
Neoplasms
Autoimmune Diseases
Colorectal Cancer
Vertigo
Bacterial Infections
Angioedemas, Hereditary
Hepatitis
Systemic Infection

Colorectal Neoplasms
Innate Immune Response
Immunologic Deficiency Syndromes
Angioedema
Sclerosis
Bacteremia
Reperfusion Injury

Pathways

Complement Activation
Pathogenesis
Immune Response
Coagulation
Localization
Phagocytosis
Innate Immune Response
Aging
Proteolysis
Inflammatory Response
Opsonization
Cellular Response To Dsrna
Regulation Of Vascular Permeability

Adaptive Immune Response
Translation
Acute-phase Response
Fibrinolysis
Cell Differentiation
Dsrna Fragmentation
Catabolic Process

PTMs

Cleavage
Acetylation
Phosphorylation

Reduction
Glycosylation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MASP2

References

PMID: 9087411 by Thiel S., et al. A second serine protease associated with mannan-binding lectin that activates complement.

PMID: 10330290 by Takahashi M., et al. A truncated form of mannose-binding lectin-associated serine protease (MASP)-2 expressed by alternative polyadenylation is a component of the lectin complement pathway.