MCCC1 Antibodies

AND MCCC1 ELISA kits, MCCC1 Proteins

Many biological assays use antibodies to detect MCCC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MCCC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MCCC1 antibodies...

We validate the specificity of these antibodies to MCCC1 by testing them on tissues known to express MCCC1 positively and negatively. Browse below to find the MCCC1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MCCC1 Infographic by Boster Bio

All MCCC1 Products

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Anti-MCCC1 Antibody Picoband®

Western blot analysis of MCCC1 using anti-MCCC1 antibody (A07441-1)

IHC analysis of MCCC1 using anti-MCCC1 antibody (A07441-1)

IF analysis of MCCC1 using anti-MCCC1 antibody (A07441-1) and anti-Beta Tubulin antibody (M01857-3)

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A07441-1
100 µg/vial

MCCC1 Overview

Facts about Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial.

MCCC1 3D structure. Source: alphafold

Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCC1)

Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme which catalyzes the conversion of 3- methylcrotonyl-CoA into 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism. .

Gene Information

Human
Gene Name:	MCCC1
Uniprot:	Q96RQ3
Entrez:	56922

Family

Belongs to:

No superfamily

Alternative Names

3-methylcrotonyl-CoA carboxylase 1; DKFZp686B20267; EC 6.4.1; EC 6.4.1.4; MCCAFLJ25545; MCC-B; methylcrotonoyl-CoA carboxylase 1 (alpha); methylcrotonoyl-Coenzyme A carboxylase 1 (alpha); mitochondrial

Molecular Weight

Mass (kDA):
80.473 kDA

Genomic Context


Human

Location:	3q27.1
Sequence:	3; NC_000003.12 (183015218..183099587, complement)

Subcellular Localizations

Mitochondrion matrix.

Diseases

Parkinson Disease
Hereditary Diseases
3-methylcrotonyl-coa Carboxylase Deficiency
Nerve Degeneration
Genetic Diseases, X-linked
Essential Tremor
Blind Vision
Asymptomatic Diseases
Deficiency Diseases

Movement Disorders
Disorder Of The Optic Nerve
Optic Atrophy, Hereditary, Leber

Pathways

Mrna Transcription
Translation
Cell Death
Aging
Pathogenesis
Glycolysis

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MCCC1

References

PMID: 11170888 by Gallardo M.E., et al. The molecular basis of 3-methylcrotonylglycinuria, a disorder of leucine catabolism.

PMID: 11401427 by Obata K., et al. Human biotin-containing subunit of 3-methylcrotonyl-CoA carboxylase gene (MCCA): cDNA sequence, genomic organization, localization to chromosomal band 3q27, and expression.