Neuromedin-U receptor 2 Antibodies

AND NMUR2 ELISA kits, Neuromedin-U receptor 2 Proteins

Many biological assays use antibodies to detect Neuromedin-U receptor 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neuromedin-U receptor 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neuromedin-U receptor 2 antibodies...

We validate the specificity of these antibodies to Neuromedin-U receptor 2 by testing them on tissues known to express NMUR2 positively and negatively. Browse below to find the NMUR2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NMUR2 Infographic by Boster Bio

All NMUR2 Products

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Anti-Neuromedin-U receptor 2 NMUR2 Antibody

Western Blot analysis of mouse-brain cells using primary antibody diluted at 1:2000 (4°C overnight)

Human, Mouse, Rat

ELISA, WB

$380
Cat # A10442
100ul

NMUR2 (NM_020167) Human Over-expression Lysate

Human

$628
Cat # LS056923
20 µg, 100 µg

NMUR2 Overview

Facts about Neuromedin-U receptor 2.

NMUR2 3D structure. Source: alphafold

Neuromedin-U receptor 2 (NMUR2)

Receptor for the neuromedin-U and neuromedin-S neuropeptides. .

Gene Information

Human
Gene Name:	NMUR2
Uniprot:	Q9GZQ4
Entrez:	56923

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

FM4; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; growth hormone secretagogue receptor family, member 4; Neuromedin U R2; neuromedin U receptor 2; Neuromedin UR2; neuromedin-U receptor 2; NMU2R; NMU2RFM-4; NMUR2; NMU-R2; TGR1; TGR-1

Molecular Weight

Mass (kDA):
47.696 kDA

Genomic Context


Human

Location:	5q33.1
Sequence:	5; NC_000005.10 (152391546..152405279, complement)

Tissue Specificity

Predominantly expressed in the CNS, particularly in the medulla oblongata, pontine reticular formation, spinal cord, and thalamus. High level in testis whereas lower levels are present in a variety of peripheral tissues including the gastrointestinal tract, genitourinary tract, liver, pancreas, adrenal gland, thyroid gland, lung, trachea, spleen and thymus.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Obesity
Neonatal Maladjustment Syndrome
Nervousness
Pain
Diabetes Mellitus
Pertussis
Metabolic Syndrome X
Pituitary Diseases
Hyperglycemia
Diabetes Mellitus, Non-insulin-dependent
Hyperalgesia
Inflammation

Dyslipidemias
Eating Disorders
Insulin Resistance
Impaired Glucose Tolerance
Dermatitis
Anxiety Disorders

Interacting Proteins

TCF4
TRAF2

Pathways

Energy Homeostasis
Regulation Of Energy Homeostasis
Secretion
Insulin Secretion
Reflex
Glucose Homeostasis
Circadian Rhythm
Somatostatin Secretion
Immune Response
Synaptic Transmission
Regulation Of Gonadotropin Secretion

Conjugation
Spermatogenesis
Gonadotropin Secretion
Pathogenesis
Regulation Of Insulin Secretion
Sensory Perception

PTMs

Oxidation

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NMUR2

References

PMID: 10887190 by Hosoya M., et al. Identification and functional characterization of a novel subtype of neuromedin U receptor.

PMID: 10899166 by Raddatz R., et al. Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system.