Histone-lysine N-methyltransferase MECOM (MECOM)

Isoform 1: Functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their saying. Oncogene which plays a role in development, cell proliferation and differentiation.

May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis.