MPDU1 Antibodies

AND MPDU1 ELISA kits, MPDU1 Proteins

Many biological assays use antibodies to detect MPDU1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MPDU1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MPDU1 antibodies...

We validate the specificity of these antibodies to MPDU1 by testing them on tissues known to express MPDU1 positively and negatively. Browse below to find the MPDU1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MPDU1 Infographic by Boster Bio

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MPDU1 (NM_004870) Human Over-expression Lysate

Human

$628
Cat # LS009526
20 µg, 100 µg

MPDU1 Overview

Facts about Mannose-P-dolichol utilization defect 1 protein.

MPDU1 3D structure. Source: alphafold

Mannose-P-dolichol utilization defect 1 protein (MPDU1)

Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors. .

Gene Information

Human
Gene Name:	MPDU1
Uniprot:	O75352
Entrez:	9526

Family

Belongs to:

MPDU1 (TC 2.A.43.3) family

Alternative Names

CDGIF; FLJ14836; HBeAg-binding protein 2 binding protein A; Lec35; mannose-P-dolichol utilization defect 1 protein; mannose-P-dolichol utilization defect 1; My008; PP3958; PQLC5; SL15HBEBP2BPA; Suppressor of Lec15 and Lec35 glycosylation mutation homolog

Molecular Weight

Mass (kDA):
26.638 kDA

Genomic Context


Human

Location:	17p13.1
Sequence:	17; NC_000017.11 (7583647..7588212)

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Congenital Disorders
Congenital Disorders Of Glycosylation
Malignant Neoplasms
Cell Transformation, Neoplastic
Malignant Squamous Cell Neoplasm
Hereditary Diseases
Failure To Thrive
Inborn Errors Of Metabolism
Dry Skin
Head And Neck Carcinoma
Exfoliative Dermatitis
Cystinosis

Carcinoma
Metabolic Diseases
Head And Neck Neoplasms
Neoplasms
Malignant Neck Neoplasm
Cleft Lip
Cleft Palate With Cleft Lip

Pathways

Glycosylation
Protein Glycosylation
Neuroprotection
Keratinocyte Differentiation
Contact Inhibition

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MPDU1

References

PMID: 9653160 by Mao M., et al. Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full- length cDNA cloning.

PMID: 11733556 by Kranz C., et al. A mutation in the human MPDU1 gene causes congenital disorder of glycosylation type If (CDG-If).