MTMR2 Antibodies

AND MTMR2 ELISA kits, MTMR2 Proteins

Many biological assays use antibodies to detect MTMR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MTMR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MTMR2 antibodies...

We validate the specificity of these antibodies to MTMR2 by testing them on tissues known to express MTMR2 positively and negatively. Browse below to find the MTMR2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MTMR2 Infographic by Boster Bio

All MTMR2 Products

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Applications

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Anti-Myotubularin-related protein 2 MTMR2 Antibody

Western blot analysis of extracts of various cell lines, using MTMR2 antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A04202
100ul

MTMR2 (NM_201281) Human Recombinant Protein

Coomassie blue staining of purified MTMR2 protein

$1249
Cat # PROTQ13614
20 µg

Anti-MTMR2 Mouse Monoclonal Antibody [Clone ID: OTI5G5]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MTMR2 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-MTMR2 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human) (1:200)

HEK293T cells transfected with either MTMR2 (Myc-DDK-tagged) overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-MTMR2 antibody (M04202)

Human, Mouse, Rat

Flow Cytometry, WB

$523
Cat # M04202
100 µl

Anti-MTMR2 Antibody Picoband®

Western blot analysis of MTMR2 using anti-MTMR2 antibody (A04202-1)

IF analysis of MTMR2 using anti-MTMR2 antibody (A04202-1)

Flow Cytometry analysis of 293T cells using anti-MTMR2 antibody (A04202-1)

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # A04202-1
100 μg/vial

MTMR2 (NM_016156) Human Over-expression Lysate

MTMR2 Human Over-expression Lysates NM_016156

Human

$628
Cat # LS008898
20 µg, 100 µg

MTMR2 Overview

Facts about Myotubularin-related protein 2.

MTMR2 3D structure. Source: alphafold

Myotubularin-related protein 2 (MTMR2)

Phosphatase that acts on lipids using a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate.

Gene Information

Human
Gene Name:	MTMR2
Uniprot:	Q13614
Entrez:	8898

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

CMT4B; CMT4B1; EC 3.1.3; EC 3.1.3.2; EC 3.1.3.48; KIAA1073EC 3.1.3.-; myotubularin related protein 2; myotubularin-related protein 2

Molecular Weight

Mass (kDA):
73.381 kDA

Genomic Context


Human

Location:	11q21
Sequence:	11; NC_000011.10 (95832880..95924110, complement)

Subcellular Localizations

Cytoplasm. Early endosome membrane; Peripheral membrane protein. Cytoplasm, perinuclear region. Cell projection, axon. Endosome membrane; Peripheral membrane protein. Partly associated with membranes (PubMed:12668758, PubMed:15998640, PubMed:21372139). Localizes to vacuoles in hypo-osmotic conditions (By similarity).

Diseases

Charcot-marie-tooth Disease
Cmt4b1
Myopathy
Congenital Structural Myopathy
Peripheral Neuropathy
Hereditary Motor And Sensory Neuropathies
Demyelination
Charcot-marie-tooth Neuropathy, Type 4b2
Nervousness
Inherited Neuropathy
Demyelinating Diseases
Sensory Neuropathy

Dejerine-sottas Disease (disorder)
Congenital Hypomyelinating Neuropathy
Muscle Hypotonia
Muscle Weakness
Weakness
Tissue Adhesions
Paresis

Interacting Proteins

NEFL

Pathways

Localization
Endocytosis
Transport
Myelination
Pathogenesis
Spermatogenesis
Mitochondrial Fusion
Cell Adhesion
Vesicle Transport
Cell Death
Single Strand Break Repair
Cell Proliferation
Cellular Process

Nerve Development
Regeneration
Mitochondrial Transport
Myelin Maintenance
Cellular Localization
Mitochondrial Fission
Rna Interference

PTMs

Dephosphorylation

Phosphorylation

Research Areas

Cancer
Protein Phosphatase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTMR2

References

PMID: 9736772 by Laporte J., et al. Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.

PMID: 8640223 by Laporte J., et al. A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast.