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- Table of Contents
MYOD1 Antibodies
AND MYOD1 ELISA kits, MYOD1 Proteins
Many biological assays use antibodies to detect MYOD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MYOD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MYOD1 antibodies...
Designing a Western blot for MYOD1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MYOD1 Western Blot GuideMYOD1 Infographic by Boster Bio
All MYOD1 Products
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MYOD1 Overview
Facts about Myoblast determination protein 1.
Myoblast determination protein 1 (MYOD1)
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis.
Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein.
Gene Information
| Human | |
|---|---|
| Gene Name: | MYOD1 |
| Uniprot: | P15172 |
| Entrez: | 4654 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
bHLHc1; bHLHc1BHLHC1; Class C basic helix-loop-helix protein 1; MYF3; MYF3Myf-3; MyoD; MYOD1; MYODmyoblast determination protein 1; myogenic differentiation 1; Myogenic factor 3myf-3; PUM
Molecular Weight
Mass (kDA):
34.501 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p15.1 |
| Sequence: | 11; NC_000011.10 (17719571..17722136) |
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Rhabdomyosarcoma
- Sarcoma
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasms
- Rhabdomyosarcoma, Embryonal
- Soft Tissue Neoplasms
- Neoplasm Metastasis
- Alveolar Rhabdomyosarcoma
- Carcinoma
- Cell Transformation, Neoplastic
- Alveolar Soft Part Sarcoma
Pathways
- Methylation
- Regeneration
- Dna Methylation
- Cell Differentiation
- Cell Proliferation
- Cell Cycle
- Myoblast Differentiation
- Localization
- Cell Adhesion
- Transport
- Myoblast Proliferation
- Muscle Cell Differentiation
- Reverse Transcription
PTMs
- Methylation
- Demethylation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYOD1
bosterbio.com/bosterbio-gene-info-cards/MYOD1
References
PMID: 1850513 by Pearson-White S.H.; Human MyoD: cDNA and deduced amino acid sequence.
PMID: 9546368 by Chen B., et al. Methylation alterations of the MyoD1 upstream region are predictive of subclassification of human rhabdomyosarcomas.