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- Table of Contents
Lactadherin Antibodies
AND MFGE8 ELISA kits, Lactadherin Proteins
Many biological assays use antibodies to detect Lactadherin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lactadherin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lactadherin antibodies...
Designing a Western blot for Lactadherin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MFGE8 Western Blot GuideMFGE8 Infographic by Boster Bio
All MFGE8 Products
Product
Figures
Specificity
Applications
Price
Human MFGE8/Lactadherin ELISA Kit PicoKine®
6 Citations
Human
ELISA
$499
Cat # EK1201
96 wells/kit, with removable strips.
Cat # EK1201
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1194
96 wells/kit, with removable strips.
Cat # EK1194
96 wells/kit, with removable strips.
Anti-Milk Fat Globule 1/MFGE8 Antibody Picoband®
1 Citations
Human
IHC, WB
$370
Cat # PA1945
100 μg/vial
Cat # PA1945
100 μg/vial
Anti-Milk Fat Globule 1/Mfge8 Antibody Picoband®
1 Citations
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A02518-1
100 μg/vial
Cat # A02518-1
100 μg/vial
MFGE8 Overview
Facts about Lactadherin.
Lactadherin (MFGE8)
Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity).
Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors.
Gene Information
| Human | |
|---|---|
| Gene Name: | MFGE8 |
| Uniprot: | Q08431 |
| Entrez: | 4240 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
BA46; Breast epithelial antigen BA46; EDIL1; hP47; HsT19888; lactadherin; Lactahedrin; Medin; MFG1; MFGE8; MFG-E8; MFGM; milk fat globule-EGF factor 8 protein; Milk fat globule-EGF factor 8; O-acetyl disialoganglioside synthase; OAcGD3S; SED1; SPAG10; sperm associated antigen 10; sperm surface protein hP47
Molecular Weight
Mass (kDA):
43.105 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q26.1 |
| Sequence: | 15; NC_000015.10 (88898683..88913405, complement) |
Tissue Specificity
Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas.
Subcellular Localizations
Membrane; Peripheral membrane protein. Secreted.
Diseases
- Inflammation
- Neoplasms
- Tissue Adhesions
- Malignant Neoplasms
- Systemic Infection
- Carcinoma
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Atherosclerosis
- Autoimmune Reaction
- Autoimmunity
- Alzheimer's Disease
- Diabetes Mellitus
Pathways
- Phagocytosis
- Apoptotic Cell Clearance
- Pathogenesis
- Secretion
- Cell Adhesion
- Coagulation
- Angiogenesis
- Lactation
- Immune Response
- Inflammatory Response
- Cell Death
- Aging
- Cell Proliferation
PTMs
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MFGE8
bosterbio.com/bosterbio-gene-info-cards/MFGE8
References
PMID: 8639264 by Couto J.R., et al. Cloning and sequence analysis of human breast epithelial antigen BA46 reveals an RGD cell adhesion sequence presented on an epidermal growth factor-like domain.
PMID: 1909932 by Larocca D., et al. A Mr 46,000 human milk fat globule protein that is highly expressed in human breast tumors contains factor VIII-like domains.
5 Publications of Boster Lactadherin Antibodies & ELISA Kits
- PubMed ID: 10.1007/s11064-018-2620-x, Intestinal Pathology and Gut Microbiota Alterations in a Methyl-4-phenyl-1,2,3,6...
- PubMed ID: 10.1007/s00592-019-01463-x, A rare missense variant in the milk fat globule-EGF factor 8 (MFGE8) increases T...
- PubMed ID: 33422097, Cai X,Li Y,Zheng X,Hu R,Li Y,Xiao L,Wang Z.Propofol suppresses microglial phagoc...
- PubMed ID: 32025861 , A rare missense variant in the milk fat globule-EGF factor 8 (MFGE8) increases T...
- PubMed ID: 26582774, Innate Immune Factors in Mothers' Breast Milk and Their Lack of Association With...
*More publications can be found for each product on its corresponding product page