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- Table of Contents
Facts about SOSS complex subunit B2.
The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent fix of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
| Human | |
|---|---|
| Gene Name: | NABP1 |
| Uniprot: | Q96AH0 |
| Entrez: | 64859 |

| Belongs to: |
|---|
| SOSS-B family |

DKFZp667M1322; FLJ13624; FLJ22833; hSSB2; MGC111163; oligonucleotide/oligosaccharide-binding fold containing 2A; Oligonucleotide/oligosaccharide-binding fold-containing protein 2A; Sensor of single-strand DNA complex subunit B2; Sensor of ssDNA subunit B2; SOSS complex subunit B2; SOSS-B2; SSB2Single-stranded DNA-binding protein 2
Mass (kDA):
22.423 kDA

| Human | |
|---|---|
| Location: | 2q32.3 |
| Sequence: | 2; NC_000002.12 (191678072..191690667) |
Nucleus. Localizes to nuclear foci following DNA damage.



PMID: 19605351 by Li Y., et al. hSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response.
PMID: 19683501 by Huang J., et al. SOSS complexes participate in the maintenance of genomic stability.