NFATC4 Antibodies

AND NFATC4 ELISA kits, NFATC4 Proteins

Many biological assays use antibodies to detect NFATC4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NFATC4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NFATC4 antibodies...

We validate the specificity of these antibodies to NFATC4 by testing them on tissues known to express NFATC4 positively and negatively. Browse below to find the NFATC4 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NFATC4 Infographic by Boster Bio

All NFATC4 Products

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Specificity

Applications

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Anti-NFATC4 Antibody Picoband®

Western blot analysis of NFATC4 using anti-NFATC4 antibody (A02599-1)

Flow Cytometry analysis of U20S cells using anti-NFATC4 antibody (A02599-1)

Flow Cytometry analysis of A431 cells using anti-NFATC4 antibody (A02599-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, ICC, WB

$370
Cat # A02599-1
100 μg/vial

NFAT3 Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from 293 cells

Human, Mouse

ELISA

$480
Cat # EKC1398
1 kit, containing one 96-well plate and all necessary reagents

NFAT3 (Phospho-Ser676) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HepG2 cells treated with Ca2+ 40uM 30

Human, Mouse

ELISA

$540
Cat # EKC2091
1 kit, containing two 96-well plates and all necessary reagents

Anti-Phospho-NFATc4 (S676) Antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A02599S676
100ul

Anti-Phospho-NFATc4 (S168/S170) Antibody

Western blot analysis of NFAT3 (Phospho-Ser168+Ser170) Antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using NFAT3 (Phospho-Ser168+Ser170) Antibody

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using NFAT3 (Phospho-Ser168+Ser170) Antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A02599S168S170
100ul

NFATC4 Overview

Facts about Nuclear factor of activated T-cells, cytoplasmic 4.

NFATC4 3D structure. Source: alphafold

Nuclear factor of activated T-cells, cytoplasmic 4 (NFATC4)

Plays a role in the inducible expression of cytokine genes in T-cells, particularly in the induction of the IL-2 and IL- 4. Transcriptionally repressed by estrogen receptors; this inhibition is further improved by estrogen.

Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation.

Gene Information

Human
Gene Name:	NFATC4
Uniprot:	Q14934
Entrez:	4776

Family

Belongs to:

No superfamily

Alternative Names

NF-AT3; NFAT3nuclear factor of activated T-cells, cytoplasmic 4; NFATc4; NF-ATc4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; T cell transcription factor NFAT3; T-cell transcription factor NFAT3

Molecular Weight

Mass (kDA):
95.449 kDA

Genomic Context


Human

Location:	14q12
Sequence:	14; NC_000014.9 (24366911..24379604)

Tissue Specificity

Highly expressed in placenta, lung, kidney, testis and ovary. Weakly expressed in spleen and thymus. Not expressed in peripheral blood lymphocytes. Detected in hippocampus.

Subcellular Localizations

Cytoplasm, cytosol. Nucleus. When hyperphosphorylated, localizes in the cytosol. When intracellular Ca(2+) levels increase, dephosphorylation by calcineurin/PPP3CA leads to translocation into the nucleus (PubMed:11997522, PubMed:18347059). MAPK7/ERK5 and MTOR regulate NFATC4 nuclear export through phosphorylation at Ser-168 and Ser-170 (PubMed:18347059).