Product Info Summary
SKU: | A02599S168S170 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-Phospho-NFATc4 (S168/S170) Antibody
SKU/Catalog Number
A02599S168S170
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-NFATc4 (S168/S170) Antibody catalog # A02599S168S170. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-NFATc4 (S168/S170) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02599S168S170)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human NFATc4 around the phosphorylation site of S168/S170.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02599S168S170 is reactive to NFATC4 in Human, Mouse
Applications
A02599S168S170 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
95.449kDa
Background of NFATC4
p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.
Tsai L.-H., Nature 371:419-423(1994).
Patrick G.N., Nature 402:615-622(1999).
Kesavapany S., J. Neurosci. 24:4421-4431(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of NFATC4 using Anti-Phospho-NFATc4 (S168/S170) Antibody (A02599S168S170).
Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100 (4°CProtein Target Info & Infographic
Gene/Protein Information For NFATC4 (Source: Uniprot.org, NCBI)
Gene Name
NFATC4
Full Name
Nuclear factor of activated T-cells, cytoplasmic 4
Weight
95.449kDa
Alternative Names
NF-AT3; NFAT3nuclear factor of activated T-cells, cytoplasmic 4; NFATc4; NF-ATc4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; T cell transcription factor NFAT3; T-cell transcription factor NFAT3 NFATC4 NF-AT3, NF-ATC4, NFAT3 nuclear factor of activated T cells 4 nuclear factor of activated T-cells, cytoplasmic 4|T-cell transcription factor NFAT3|nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NFATC4, check out the NFATC4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NFATC4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-NFATc4 (S168/S170) Antibody (A02599S168S170)
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No publications found for A02599S168S170
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