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- Table of Contents
Podocin Antibodies
AND NPHS2 ELISA kits, Podocin Proteins
Many biological assays use antibodies to detect Podocin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Podocin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Podocin antibodies...
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NPHS2 Infographic by Boster Bio
All NPHS2 Products
Product
Figures
Specificity
Applications
Price
Anti-Podocin NPHS2 Antibody Picoband®
2 Citations 7 Q&As
Human, Mouse, Rat
WB
$370
Cat # PA1322
100 μg/vial
Cat # PA1322
100 μg/vial
Anti-Podocin NPHS2 Antibody Picoband®
12 Citations 1 Q&As
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1322-1
100 μg/vial
Cat # PA1322-1
100 μg/vial
NPHS2 Overview
Facts about Podocin.
Podocin (NPHS2)
Plays a role in the regulation of glomerular permeability, acting likely as a linker between the plasma membrane and the cytoskeleton. .
Gene Information
| Human | |
|---|---|
| Gene Name: | NPHS2 |
| Uniprot: | Q9NP85 |
| Entrez: | 7827 |
Family
| Belongs to: |
|---|
| band 7/mec-2 family |
Alternative Names
Nephrosis 2; nephrosis 2, idiopathic, steroid-resistant (podocin); NPHS2; PDCN; PDCNSRN1podocin; Podocin; SRN1
Molecular Weight
Mass (kDA):
42.201 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q25.2 |
| Sequence: | 1; NC_000001.11 (179550539..179575987, complement) |
Tissue Specificity
Almost exclusively expressed in the podocytes of fetal and mature kidney glomeruli.
Subcellular Localizations
[Isoform 1]: Cell membrane; Peripheral membrane protein.; [Isoform 2]: Endoplasmic reticulum.
Diseases
- Nephrotic Syndrome
- Steroid-resistant Nephrotic Syndrome
- Focal Glomerulosclerosis
- Glomerulosclerosis (disorder)
- Proteinuria Of Undiagnosed Cause
- Kidney Diseases
- Segmental Glomerulosclerosis
- Kidney Failure, Chronic
- Kidney Failure
- Congenital Nephrotic Syndrome
- Lipoid Nephrosis
- Sclerosis
- Glomerulonephritis, Minimal Change
Interacting Proteins
- IQGAP1
Pathways
- Glomerular Filtration
- Pathogenesis
- Localization
- Excretion
- Secretory Pathway
- Oxidative Phosphorylation
- Regeneration
- Sperm Motility
- Cell Death
- Axon Guidance
- Protein Folding
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NPHS2
bosterbio.com/bosterbio-gene-info-cards/NPHS2
References
PMID: 10742096 by Boute N., et al. NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome.
PMID: 11562357 by Huber T.B., et al. Interaction with podocin facilitates nephrin signaling.
8 Publications of Boster Podocin Antibodies & ELISA Kits
- PubMed ID: 31301369, Qiu Y,Zhou J,Zhang H,Zhou H,Tang H,Lei C,Ye C,You C,Chen Y,Wang Y,Xiong J,Su H,Y...
- PubMed ID: 33537831, Zhang X,Zhang L,Chen Z,Li S,Che B, Wang N,Chen J,Xu C,Wei C.Exogenous spermine a...
- PubMed ID: 32307498, Qi MY,Wang XT,Xu HL,Yang ZL,Cheng Y,Zhou B.Protective effect of ferulic acid on ...
- PubMed ID: 32908940, Liao H,Li Y,Zhang X,Zhao X,Zheng D,Shen D,Li R. Protective Effects of Thalidomid...
- PubMed ID: 33186558, Fu Y, Sun Y, Wang M, Hou Y, Huang W, Zhou D, Wang Z, Yang S, Tang W, Zhen J, Li ...
- PubMed ID: 26770424, Effect of simvastatin on the expression of nephrin, podocin, and vascular endoth...
- PubMed ID: 24926327, Hao L, Pan Ms, Zheng Y, Wang Rf. Exp Ther Med. 2014 Jun;7(6):1465-1470. Epub 201...
- PubMed ID: 23573468, Qu Y, Du E, Zhang Y, Li S, Han R, Qiu M. Nephrourol Mon. 2012 Spring;4(2):466-9....
*More publications can be found for each product on its corresponding product page