Nuclear receptor-interacting protein 1 (NRIP1)

Modulates transcriptional activation by steroid receptors like NR3C1, NR3C2 and ESR1. Additionally modulates transcriptional repression by nuclear hormone receptors.

Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. .