NRIP1 Antibodies

AND NRIP1 ELISA kits, NRIP1 Proteins

Many biological assays use antibodies to detect NRIP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NRIP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NRIP1 antibodies...

We validate the specificity of these antibodies to NRIP1 by testing them on tissues known to express NRIP1 positively and negatively. Browse below to find the NRIP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NRIP1 Infographic by Boster Bio

All NRIP1 Products

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Specificity

Applications

Price

RIP140 (NRIP1) (NM_003489) Human Over-expression Lysate

Human

$628
Cat # LS008204
20 µg, 100 µg

Anti-NRIP1 Antibody Picoband®

Human, Mouse

ELISA, IHC, WB

$370
Cat # A02919
100 μg/vial

NRIP1 Overview

Facts about Nuclear receptor-interacting protein 1.

NRIP1 3D structure. Source: alphafold

Nuclear receptor-interacting protein 1 (NRIP1)

Modulates transcriptional activation by steroid receptors like NR3C1, NR3C2 and ESR1. Additionally modulates transcriptional repression by nuclear hormone receptors.

Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. .

Gene Information

Human
Gene Name:	NRIP1
Uniprot:	P48552
Entrez:	8204

Family

Belongs to:

No superfamily

Alternative Names

10RIP140Receptor-interacting protein 140; FLJ77253; nuclear receptor interacting protein 1; nuclear receptor-interacting protein 1; receptor interacting protein 140

Molecular Weight

Mass (kDA):
126.942 kDA

Genomic Context


Human

Location:	21q11.2-q21.1
Sequence:	21; NC_000021.9 (14961235..15065903, complement)

Subcellular Localizations

Nucleus. Localized to discrete foci and redistributes to larger nuclear domains upon binding to ligand-bound NR3C1.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Infertility
Leukemia
Carcinoma
Osteoporosis
Anovulation
Osteoporosis, Postmenopausal
Trisomy
Carcinogenesis

Neoplasm Metastasis
Mutation, Out-of-frame
Embryonal Carcinoma
Down Syndrome
Migraine With Aura
Oncogene Fusion

Interacting Proteins

ARPC3
CEP70
CTBP1
DNMT1
FHL1

HDAC3
LDOC1
PRMT1
RARA
ZNF366

Pathways

Ovulation
Cell Differentiation
Parturition
Cell Growth
Stem Cell Differentiation
Mammary Gland Morphogenesis
Regulation Of Gene Expression
Mammary Gland Development
Inflammatory Response
Reverse Transcription
Cell Cycle
Cell Motility
Interphase

Gland Morphogenesis
Cell Proliferation
Gland Development
Lactation
Glucocorticoid Secretion
Menopause
Energy Homeostasis

PTMs

Sumoylation

Research Areas

Transcription Factors and Regulators

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NRIP1

References

PMID: 7641693 by Cavailles V., et al. Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.

PMID: 9556573 by Yan Z.H., et al. Regulation of peroxisome proliferator-activated receptor alpha- induced transactivation by the nuclear orphan receptor TAK1/TR4.