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Neurexin-1-beta Antibodies

AND NRXN1 ELISA kits, Neurexin-1-beta Proteins

Many biological assays use antibodies to detect Neurexin-1-beta, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neurexin-1-beta in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neurexin-1-beta antibodies...

We validate the specificity of these antibodies to Neurexin-1-beta by testing them on tissues known to express NRXN1 positively and negatively. Browse below to find the NRXN1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NRXN1 Infographic by Boster Bio

NRXN1 protein infographic

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Anti-Neurexin 1/NRXN1 Antibody Picoband®

Western blot analysis of Neurexin 1/NRXN1 using anti-Neurexin 1/NRXN1 antibody (A01490-1)

Western blot analysis of Neurexin 1/NRXN1 using anti-Neurexin 1/NRXN1 antibody (A01490-1)

Flow Cytometry analysis of SH-SY5Y cells using anti-Neurexin 1/NRXN1 antibody (A01490-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A01490-1
100 μg/vial

NRXN1 Overview

Facts about Neurexin-1-beta.

NRXN1 3D structure

NRXN1 3D structure. Source: alphafold

Neurexin-1-beta (NRXN1)

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions.

May mediate intracellular signaling. May play a role in angiogenesis (By similarity).

Gene Information

Human
Gene Name:	NRXN1
Uniprot:	P58400
Entrez:	9378

Gene Information

Family

Belongs to:

neurexin family

Family

Alternative Names

Neurexin 1 beta; NXR1B; NXRN1b

Molecular Weight

Mass (kDA):
50.424 kDA

Molecular Weight

Genomic Context


Human

Location:	2p16.3
Sequence:	2; NC_000002.12 (49918503..51032536, complement)

Subcellular Localizations

Cell junction, synapse, presynaptic cell membrane; Single-pass type I membrane protein.

Subcellular Localization

Diseases

Autistic Disorder
Schizophrenia
Autism Spectrum Disorders
Tissue Adhesions
Mental Disorders
Epilepsy
Child Development Disorders, Pervasive
Nicotine Dependence
Nervousness
Cytogenetic Abnormality
Bipolar Disorder
Developmental Disabilities

Language Development Disorders
Cognition Disorders
Brain Diseases
Impaired Cognition
Alzheimer's Disease
Malnutrition

Disease

Pathways

Cell Adhesion
Synaptic Transmission
Pathogenesis
Cognition
Brain Development
Neurogenesis
Translation
System Development
Localization
Nervous System Development
Transport
Cellular Response To Dsrna
Habituation

Cell Fate Determination
Grooming Behavior
Cell Differentiation
Dsrna Fragmentation
Catabolic Process
Prepulse Inhibition
Response To Dsrna

Pathways

PTMs

Cleavage

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NRXN1

References

PMID: 9921901 by Kleiderlein J.J., et al. CCG repeats in cDNAs from human brain.

PMID: 20090838 by Barbu E.M., et al. beta-Neurexin is a ligand for the Staphylococcus aureus MSCRAMM SdrC.