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- Table of Contents
Facts about Ninein.
May play a role in microtubule nucleation, by recruiting the gamma-tubulin ring complex to the centrosome (PubMed:15784680). Overexpression doesn't perturb nucleation or elongation of microtubules but suppresses release of microtubules (By similarity).
| Mouse | |
|---|---|
| Gene Name: | Nin |
| Uniprot: | Q61043 |
| Entrez: | 18080 |

| Belongs to: |
|---|
| No superfamily |

Glycogen synthase kinase 3 beta-interacting protein; GSK3B-interacting protein; hNinein; KIAA1565; ninein (GSK3B interacting protein); ninein centrosomal protein; ninein
Mass (kDA):
243.718 kDA

| Mouse | |
|---|---|
| Location: | 12|12 C2 |
| Sequence: | 12; |
Widely expressed. Highly expressed in spleen, bone marrow and skin. Weakly expressed in liver and small intestine. Expressed in brain.



PMID: 8834802 by Bouckson-Castaing V., et al. Molecular characterisation of ninein, a new coiled-coil protein of the centrosome.
PMID: 15784680 by Delgehyr N., et al. Microtubule nucleation and anchoring at the centrosome are independent processes linked by ninein function.