PAOX Antibodies

AND PAOX ELISA kits, PAOX Proteins

Many biological assays use antibodies to detect PAOX, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PAOX in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PAOX antibodies...

We validate the specificity of these antibodies to PAOX by testing them on tissues known to express PAOX positively and negatively. Browse below to find the PAOX antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PAOX Infographic by Boster Bio

All PAOX Products

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Product

Figures

Specificity

Applications

Price

Anti-PAOX Antibody

4 Q&As

Western Blot analysis of extracts from rat stomach, K562 cells, using PAOX Polyclonal Antibody

Human, Mouse

ELISA, IF, IHC, WB

$399
Cat # A08936
100μl

PAOX (NM_207128) Human Recombinant Protein

Coomassie blue staining of purified PAOX protein

$1062
Cat # PROTQ6QHF9
20 µg

PAOX (NM_207127) Human Over-expression Lysate

PAOX Human Over-expression Lysates NM_152911

Human

$628
Cat # LS196743
20 µg, 100 µg

PAOX Overview

Facts about Peroxisomal N(1)-acetyl-spermine/spermidine oxidase.

PAOX 3D structure. Source: alphafold

Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (PAOX)

Flavoenzyme that catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine.

Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine.

Gene Information

Human
Gene Name:	PAOX
Uniprot:	Q6QHF9
Entrez:	196743

Family

Belongs to:

flavin monoamine oxidase family

Alternative Names

DKFZp434J245; MGC45464; PAO; polyamine oxidase (exo-N4-amino); polyamine oxidase

Molecular Weight

Mass (kDA):
55.513 kDA

Genomic Context


Human

Location:	10q26.3
Sequence:	10; NC_000010.11 (133379262..133391694)

Tissue Specificity

Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues.

Subcellular Localizations

Peroxisome. Cytoplasm.

Diseases

Prion Diseases
Drug-induced Liver Injury
Neurodegenerative Disorders
Liver Failure
Inflammation
Liver Failure, Acute

Pathways

Protein Import
Fermentation
Proteolysis

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PAOX

References

PMID: 12660232 by Wu T., et al. Cloning, sequencing, and heterologous expression of the murine peroxisomal flavoprotein, N(1)-acetylated polyamine oxidase.

PMID: 12477380 by Vujcic S., et al. Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion.