Protein PAT1 homolog 1 Antibodies

AND PATL1 ELISA kits, Protein PAT1 homolog 1 Proteins

Many biological assays use antibodies to detect Protein PAT1 homolog 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein PAT1 homolog 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein PAT1 homolog 1 antibodies...

We validate the specificity of these antibodies to Protein PAT1 homolog 1 by testing them on tissues known to express PATL1 positively and negatively. Browse below to find the PATL1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: OOSP2

PATL1 Infographic by Boster Bio

All PATL1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

PATL1 (NM_152716) Human Over-expression Lysate

Human

$628
Cat # LS219988
20 µg, 100 µg

PATL1 Overview

Facts about Protein PAT1 homolog 1.

PATL1 3D structure. Source: alphafold

Protein PAT1 homolog 1 (PATL1)

RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery.

Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).

Gene Information

Human
Gene Name:	PATL1
Uniprot:	Q86TB9
Entrez:	219988

Family

Belongs to:

PAT1 family

Alternative Names

FLJ36874; hPat1b; MGC125671; OK/KNS-cl.5; Pat1b; PAT1-like protein 1; protein associated with topoisomerase II homolog 1 (yeast); protein PAT1 homolog 1; protein PAT1 homolog b

Molecular Weight

Mass (kDA):
86.85 kDA

Genomic Context


Human

Location:	11q12.1
Sequence:	11; NC_000011.10 (59636716..59669037, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm, P-body. Nucleus. Nucleus, PML body. Nucleus speckle. Predominantly cytoplasmic. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Enriched in splicing speckles. Localization to nuclear foci and speckles requires active transcription. Excluded from the nucleolus.

Diseases

Hepatitis
Hepatitis C
Virus Diseases

Interacting Proteins

FHL3
GOLGA2
PSMA3

Pathways

Translation
Cytokinesis
Transport
Response To Heat
Localization
Nuclear Export

Oogenesis

PTMs

Biotinylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PATL1

References

PMID: 17936923 by Scheller N., et al. Identification of PatL1, a human homolog to yeast P body component Pat1.

PMID: 19628699 by Scheller N., et al. Translation and replication of hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fates.