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- Table of Contents
Paired box protein Pax-3 Antibodies
AND PAX3 ELISA kits, Paired box protein Pax-3 Proteins
Many biological assays use antibodies to detect Paired box protein Pax-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Paired box protein Pax-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Paired box protein Pax-3 antibodies...
Designing a Western blot for Paired box protein Pax-3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PAX3 Western Blot GuidePAX3 Infographic by Boster Bio
All PAX3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00285-1
100 μg/vial
Cat # A00285-1
100 μg/vial
PAX3 Overview
Facts about Paired box protein Pax-3.
Paired box protein Pax-3 (PAX3)
Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis.
Transcriptional activator of MITF, acting synergistically with SOX10 (PubMed:21965087). .
Gene Information
| Human | |
|---|---|
| Gene Name: | PAX3 |
| Uniprot: | P23760 |
| Entrez: | 5077 |
Family
| Belongs to: |
|---|
| paired homeobox family |
Alternative Names
CDHS; HUP2; HUP2MGC120384; MGC120381; MGC120382; MGC120383; MGC134778; paired box 3; paired box gene 3 (Waardenburg syndrome 1); paired box homeotic gene 3; paired box protein Pax-3; paired domain gene 3; paired domain gene HuP2; Pax3; Waardenburg syndrome 1; WS1; WS3
Molecular Weight
Mass (kDA):
52.968 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q36.1 |
| Sequence: | 2; NC_000002.12 (222199887..222298998, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Rhabdomyosarcoma
- Neoplasms
- Crest Syndrome
- Alveolar Rhabdomyosarcoma
- Waardenburg Syndrome
- Chromosomal Translocation
- Malignant Neoplasms
- Rhabdomyosarcoma, Embryonal
- Waardenburg Syndrome, Type I (disorder)
- Melanoma
- Cell Transformation, Neoplastic
- Sarcoma
Interacting Proteins
- POU3F2
- SOX10
Pathways
- Regeneration
- Cell Proliferation
- Neural Tube Closure
- Tube Closure
- Cell Differentiation
- Neurogenesis
- Pigmentation
- Cell Migration
- Cell Death
- Pathogenesis
- Cell Cycle
- Localization
- Delamination
PTMs
- Phosphorylation
- Methylation
- Acetylation
- Cleavage
- Ubiquitination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PAX3
bosterbio.com/bosterbio-gene-info-cards/PAX3
References
PMID: 14639621 by Parker C.J., et al. Expression of PAX 3 alternatively spliced transcripts and identification of two new isoforms in human tumors of neural crest origin.
PMID: 7782066 by Macina R.A., et al. Genomic organization of the human PAX3 gene: DNA sequence analysis of the region disrupted in alveolar rhabdomyosarcoma.
1 Publications of Boster Paired box protein Pax-3 Antibodies & ELISA Kits
- PubMed ID: 24126784, Zhang Rp, Liu Hh, Wang Hh, Wang Y, Han Cc, Li L, He H, Xu Hy, Xu F, Wang Jw. Mol...
*More publications can be found for each product on its corresponding product page