PCK2 Antibodies

AND PCK2 ELISA kits, PCK2 Proteins

Many biological assays use antibodies to detect PCK2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PCK2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PCK2 antibodies...

We validate the specificity of these antibodies to PCK2 by testing them on tissues known to express PCK2 positively and negatively. Browse below to find the PCK2 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PCK2 Infographic by Boster Bio

All PCK2 Products

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Anti-PCK2 Monoclonal Antibody

7 Q&As

Western blot analysis of PCK2 using anti-PCK2 antibody (M04772)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M04772
100 μl

Anti-PCK2 Antibody Picoband®

Western blot analysis of PCK2 using anti-PCK2 antibody (A04772-1)

IHC analysis of PCK2 using anti-PCK2 antibody (A04772-1)

+10

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04772-1
100 μg/vial

Anti-PCK2 Antibody

Human, Mouse, Rat

$405
Cat # A04772
100ul

Anti-PCK2 Antibody

ICC staining PCK2 in HepG2 cells (green)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$405
Cat # A04772-2
100ul

Anti-PCK2 Antibody Picoband® (monoclonal, 3F7)

1 Citations

Western blot analysis of PCK2 using anti-PCK2 antibody (M04772-2)

IHC analysis of PCK2 using anti-PCK2 antibody (M04772-2)

Human, Monkey, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M04772-2
100 μg/vial

PCK2 (NM_004563) Human Over-expression Lysate

PCK2 Human Over-expression Lysates NM_001018073

Human

$628
Cat # LS005106
20 µg, 100 µg

PCK2 Overview

Facts about Phosphoenolpyruvate carboxykinase [GTP], mitochondrial.

PCK2 3D structure. Source: alphafold

Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2)

Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway which produces glucose from lactate and other precursors derived from the citric acid cycle. .

Gene Information

Human
Gene Name:	PCK2
Uniprot:	Q16822
Entrez:	5106

Family

Belongs to:

phosphoenolpyruvate carboxykinase [GTP] family

Alternative Names

EC 4.1.1.32; PE; PEPCK; PEPCK2PEP carboxykinase; PEPCK-M; phosphoenolpyruvate carboxykinase [GTP], mitochondrial; phosphoenolpyruvate carboxykinase 2 (mitochondrial); Phosphoenolpyruvate carboxylase; phosphopyruvate carboxylase

Molecular Weight

Mass (kDA):
70.699 kDA

Genomic Context


Human

Location:	14q11.2-q12
Sequence:	14; NC_000014.9 (24094311..24104125)

Subcellular Localizations

Mitochondrion.

Diseases

Diabetes Mellitus
Obesity
Diabetes Mellitus, Non-insulin-dependent
Insulin Resistance
Hyperglycemia
Neoplasms
Hypoglycemia
Liver Carcinoma
Sclerosis
Hydrocephalus, Normal Pressure
Intraepithelial Neoplasia
Thymoma
Endometrial Polyp

Hypoxia
Carcinoma
Fetal Growth Retardation
Hypokinesia
Carcinoma In Situ
Malignant Neoplasms
Gestational Diabetes

Interacting Proteins

SMAD3

Pathways

Gluconeogenesis
Localization
Cell Cycle
Cell Growth
Transport
Hypersensitivity
Cytokinesis
Glucose Homeostasis
Cell Morphogenesis
Cell Proliferation
Regeneration
Sporulation
Regulation Of Actin Cytoskeleton Organization

Cytoskeleton Organization
Flight
Reverse Transcription
Translation
Mrna Transcription
Lipid Homeostasis
Mating

PTMs

Phosphorylation

Glycosylation

Dephosphorylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PCK2

References

PMID: 8645161 by Modaressi S., et al. Molecular cloning, sequencing and expression of the cDNA of the mitochondrial form of phosphoenolpyruvate carboxykinase from human liver.

PMID: 9657976 by Modaressi S., et al. Human mitochondrial phosphoenolpyruvate carboxykinase 2 gene. Structure, chromosomal localization and tissue-specific expression.