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- Table of Contents
PCK2 Antibodies
AND PCK2 ELISA kits, PCK2 Proteins
Many biological assays use antibodies to detect PCK2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PCK2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PCK2 antibodies...
Designing a Western blot for PCK2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PCK2 Western Blot GuideDesigning an IHC experiment for PCK2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PCK2 IHC GuidePCK2 Infographic by Boster Bio
All PCK2 Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A04772-1
100 μg/vial
Cat # A04772-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A04777-2
100 μg/vial
Cat # A04777-2
100 μg/vial
Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M04772-2
100 μg/vial
Cat # M04772-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M04772
100 μl
Cat # M04772
100 μl
PCK2 Overview
Facts about Phosphoenolpyruvate carboxykinase [GTP], mitochondrial.
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2)
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway which produces glucose from lactate and other precursors derived from the citric acid cycle. .
.
Gene Information
| Human | |
|---|---|
| Gene Name: | PCK2 |
| Uniprot: | Q16822 |
| Entrez: | 5106 |
Family
| Belongs to: |
|---|
| phosphoenolpyruvate carboxykinase [GTP] family |
Alternative Names
EC 4.1.1.32; PE; PEPCK; PEPCK2PEP carboxykinase; PEPCK-M; phosphoenolpyruvate carboxykinase [GTP], mitochondrial; phosphoenolpyruvate carboxykinase 2 (mitochondrial); Phosphoenolpyruvate carboxylase; phosphopyruvate carboxylase
Molecular Weight
Mass (kDA):
70.699 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q11.2-q12 |
| Sequence: | 14; NC_000014.9 (24094311..24104125) |
Subcellular Localizations
Mitochondrion.
Diseases
- Diabetes Mellitus
- Obesity
- Diabetes Mellitus, Non-insulin-dependent
- Insulin Resistance
- Hyperglycemia
- Neoplasms
- Hypoglycemia
- Liver Carcinoma
- Sclerosis
- Hydrocephalus, Normal Pressure
- Intraepithelial Neoplasia
- Thymoma
- Endometrial Polyp
Interacting Proteins
- SMAD3
Pathways
- Gluconeogenesis
- Localization
- Cell Cycle
- Cell Growth
- Transport
- Hypersensitivity
- Cytokinesis
- Glucose Homeostasis
- Cell Morphogenesis
- Cell Proliferation
- Regeneration
- Sporulation
- Regulation Of Actin Cytoskeleton Organization
PTMs
- Phosphorylation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PCK2
bosterbio.com/bosterbio-gene-info-cards/PCK2
References
PMID: 8645161 by Modaressi S., et al. Molecular cloning, sequencing and expression of the cDNA of the mitochondrial form of phosphoenolpyruvate carboxykinase from human liver.
PMID: 9657976 by Modaressi S., et al. Human mitochondrial phosphoenolpyruvate carboxykinase 2 gene. Structure, chromosomal localization and tissue-specific expression.