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- Table of Contents
Progesterone receptor Antibodies
AND PGR ELISA kits, Progesterone receptor Proteins
Many biological assays use antibodies to detect Progesterone receptor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Progesterone receptor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Progesterone receptor antibodies...
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PGR Infographic by Boster Bio
All PGR Products
Product
Figures
Specificity
Applications
Price
Anti-Progesterone Receptor/PGR Antibody Picoband®
1 Citations 1 Q&As
Human
IHC, WB
$370
Cat # PA1413
100 μg/vial
Cat # PA1413
100 μg/vial
Anti-Progesterone Receptor/PGR Antibody Picoband®
6 Citations 3 Q&As
Human
IF, IHC, ICC, WB
$370
Cat # PB9009
100 μg/vial
Cat # PB9009
100 μg/vial
Human
IP, IF, IHC, ICC, WB
$370
Cat # M00541-1
100 μl
Cat # M00541-1
100 μl
Human
IHC, WB
$449
Cat # M00541-3
100uL
Cat # M00541-3
100uL
Human
ELISA
$480
Cat # EKC1484
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1484
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2112
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2112
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA
$540
Cat # EKC2113
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2113
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA
$540
Cat # EKC2497
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2497
1 kit, containing two 96-well plates and all necessary reagents
Human
Flow Cytometry, IHC, WB
$523
Cat # M00541-4
100 µl
Cat # M00541-4
100 µl
Human, Monkey, Mouse, Rat
IF, ICC, WB
$370
Cat # P00541-2
100 μl/vial
Cat # P00541-2
100 μl/vial
PGR Overview
Facts about Progesterone receptor.
Progesterone receptor (PGR)
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Based on the isoform, progesterone receptor functions as transcriptional activator or repressor.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | PGR |
| Uniprot: | P06401 |
| Entrez: | 5241 |
Family
| Belongs to: |
|---|
| nuclear hormone receptor family |
Alternative Names
NR3C3; NR3C3PRNuclear receptor subfamily 3 group C member 3; PGR; Progesterone R; progesterone receptor; ProgesteroneR
Molecular Weight
Mass (kDA):
98.981 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q22.1 |
| Sequence: | 11; NC_000011.10 (101029624..101130681, complement) |
Tissue Specificity
In reproductive tissues the expression of isoform A and isoform B varies as a consequence of developmental and hormonal status. Isoform A and isoform B are expressed in comparable levels in uterine glandular epithelium during the proliferative phase of the menstrual cycle. Expression of isoform B but not of isoform A persists in the glands during mid-secretory phase. In the stroma, isoform A is the predominant form throughout the cycle. Heterogeneous isoform expression between the glands of the endometrium basalis and functionalis is implying region- specific responses to hormonal stimuli.
Subcellular Localizations
Nucleus. Cytoplasm. Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases.; [Isoform A]: Nucleus. Cytoplasm. Mainly nuclear.; [Isoform 4]: Mitochondrion outer membrane.
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Neoplasms
- Carcinoma
- Endometrial Polyp
- Adenocarcinoma
- Leukemia
- Ovarian Neoplasm
- Malignant Paraganglionic Neoplasm
- Neoplasm Metastasis
- Malignant Neoplasm Of Ovary
- Endometrial Carcinoma
Interacting Proteins
- CUEDC2
- ESR1
- STAT3
Pathways
- Ovulation
- Methylation
- Secretion
- Localization
- Dna Methylation
- Cell Proliferation
- Pathogenesis
- Embryo Implantation
- Fertilization
- Regeneration
- Transport
- Parturition
- Cell Growth
PTMs
- Methylation
- Phosphorylation
- Cleavage
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PGR
bosterbio.com/bosterbio-gene-info-cards/PGR
References
PMID: 2328727 by Kastner P., et al. Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.
PMID: 3551956 by Misrahi M., et al. Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA.
7 Publications of Boster Progesterone receptor Antibodies & ELISA Kits
- PubMed ID: 10.5582/bst.2015.01161, Overexpression of C35 in breast carcinomas is associated with tumor progression ...
- PubMed ID: 10.2147/DDDT.S297236, Effect of Oral versus Vaginal Administration of Estradiol and Dydrogesterone on ...
- PubMed ID: 10.1095/biolreprod.104.032821, A Model for Implantation: Coculture of Blastocysts and Uterine Endometrium in Mi...
- PubMed ID: 10.1038/modpathol.2009.25, Aberrant survivin expression in endometrial hyperplasia: another mechanism of pr...
- PubMed ID: 10.1007/s11596-011-0248-z, Impact of luteinized unruptured follicles on endometrial receptivity
- PubMed ID: 10.1002/jcla.21911, Circulating Tumor Cells and Tumor Stem Cells Detection in the Peripheral Blood M...
- PubMed ID: 22101081, Fu Y, Zhao Z, Wu Y, Wu K, Xu X, Liu Y, Tong C. J Ethnopharmacol. 2012 Jan 6;139(...
*More publications can be found for each product on its corresponding product page