PIGL Antibodies

AND PIGL ELISA kits, PIGL Proteins

Many biological assays use antibodies to detect PIGL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PIGL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PIGL antibodies...

We validate the specificity of these antibodies to PIGL by testing them on tissues known to express PIGL positively and negatively. Browse below to find the PIGL antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PIGL Infographic by Boster Bio

All PIGL Products

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Specificity

Applications

Price

PIGL (NM_004278) Human Recombinant Protein

Coomassie blue staining of purified PIGL protein

$1249
Cat # PROTQ9Y2B2
20 µg

PIGL (NM_004278) Human Over-expression Lysate

Human

$628
Cat # LS009487
20 µg, 100 µg

PIGL Overview

Facts about N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase.

PIGL 3D structure. Source: alphafold

N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (PIGL)

Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol.

Gene Information

Human
Gene Name:	PIGL
Uniprot:	Q9Y2B2
Entrez:	9487

Family

Belongs to:

PIGL family

Alternative Names

EC 3.5.1.89; N-acetylglucosaminylphosphatidylinositol deacetylase; N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; phosphatidylinositol glycan anchor biosynthesis, class L; phosphatidylinositol glycan, class L; Phosphatidylinositol-glycan biosynthesis class L protein; PIG-L

Molecular Weight

Mass (kDA):
28.531 kDA

Genomic Context


Human

Location:	17p11.2
Sequence:	17; NC_000017.11 (16217209..16351800)

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass membrane protein.

Diseases

Burkitt Lymphoma
Congenital Ocular Coloboma (disorder)
Ichthyoses
Zunich Neuroectodermal Syndrome
Protein Deficiency
Conductive Hearing Loss
Gastritis
Neurocutaneous Syndromes
Congenital Heart Defects

Persistent Superficial Gastritis
Lymphoma
Dermatologic Disorders

Pathways

Transport
Dna Replication
Oxidative Phosphorylation
Pathogenesis

PTMs

Gpi Anchoring
Phosphorylation

Methylation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PIGL

References

PMID: 10085243 by Watanabe R., et al. Mammalian PIG-L and its yeast homologue Gpi12p are N- acetylglucosaminylphosphatidylinositol de-N-acetylases essential in glycosylphosphatidylinositol biosynthesis.

PMID: 22444671 by Ng B.G., et al. Mutations in the glycosylphosphatidylinositol gene PIGL cause CHIME syndrome.