PLA2G7 Antibodies

AND PLA2G7 ELISA kits, PLA2G7 Proteins

Many biological assays use antibodies to detect PLA2G7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLA2G7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLA2G7 antibodies...

We validate the specificity of these antibodies to PLA2G7 by testing them on tissues known to express PLA2G7 positively and negatively. Browse below to find the PLA2G7 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLA2G7 Infographic by Boster Bio

All PLA2G7 Products

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Product

Figures

Specificity

Applications

Price

Human PLA2G7/Lp-PLA2 ELISA Kit PicoKine®

1 Citations 7 Q&As

Human

ELISA

$499
Cat # EK1637
96 wells/kit, with removable strips.

Anti-PAFAH/PLA2G7 Antibody Picoband®

5 Q&As

Western blot analysis of PAFAH using anti-PAFAH antibody (A02164-2)

Human

WB, ELISA (Cap)

$370
Cat # A02164-2
100 μg/vial

Anti-PLA2G7 Antibody

Western blot analysis of extracts of Rat serum, using PLA2G7 Rabbit pAb at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A02164
100ul

PAFAH (PLA2G7) (NM_001168357) Human Recombinant Protein

$1296
Cat # PROTQ13093
20 µg

PAFAH (PLA2G7) (NM_005084) Human Over-expression Lysate

Human

$628
Cat # LS007941
20 µg, 100 µg

PLA2G7 Overview

Facts about Platelet-activating factor acetylhydrolase.

PLA2G7 3D structure. Source: alphafold

Platelet-activating factor acetylhydrolase (PLA2G7)

Modulates the activity of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates using a short residue at the sn-2 position.

It's inactive against long-chain phospholipids. .

Gene Information

Human
Gene Name:	PLA2G7
Uniprot:	Q13093
Entrez:	7941

Family

Belongs to:

AB hydrolase superfamily

Alternative Names

2-acetyl-1-alkylglycerophosphocholine esterase; EC 3.1.1; EC 3.1.1.47,1-alkyl-2-acetylglycerophosphocholine esterase; Group-VIIA phospholipase A2; gVIIA-PLA2; LDL-associated phospholipase A2; LDL-PLA(2); LDL-PLA2; lipoprotein-associated phospholipase A2; LpPLA2; Lp-PLA2; PAF acetylhydrolase; PAF-AH; PAFAHPAF 2-acylhydrolase; phospholipase A2, group VII (platelet-activating factor acetylhydrolase; PLA2G7; plasma); platelet-activating factor acetylhydrolase

Molecular Weight

Mass (kDA):
50.077 kDA

Genomic Context


Human

Location:	6p12.3
Sequence:	6; NC_000006.12 (46700558..46735836, complement)

Tissue Specificity

Plasma.

Subcellular Localizations

Secreted, extracellular space.

Diseases

Coronary Artery Disease
Cardiovascular Diseases
Atherosclerosis
Inflammation
Coronary Heart Disease
Heart Diseases
Malignant Neoplasms
Diabetes Mellitus
Infarction
Myocardial Infarction
Dental Plaque
Prostatic Neoplasms

Malignant Neoplasm Of Prostate
Obesity
Neoplasms
Dysequilibrium Syndrome
Schizophrenia
Hypertensive Disease
Hyperlipidemia

Pathways

Pathogenesis
Aging
Cell Death
Immune Response
Vasodilation
Acute Inflammatory Response
Cell Migration
Programmed Cell Death
Brain Development
Chromosome Segregation
Macrophage Activation
Inflammatory Response

Macrophage Differentiation
Cell Cycle
Cell Differentiation
Cell Growth
Rna Interference
Secretion

PTMs

Oxidation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLA2G7

References

PMID: 7700381 by Tjoelker L.W., et al. Anti-inflammatory properties of a platelet-activating factor acetylhydrolase.

PMID: 8624782 by Tew D.G., et al. Purification, properties, sequencing, and cloning of a lipoprotein- associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins.