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- Table of Contents
Phospholipase D1 Antibodies
AND PLD1 ELISA kits, Phospholipase D1 Proteins
Many biological assays use antibodies to detect Phospholipase D1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Phospholipase D1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Phospholipase D1 antibodies...
Designing a Western blot for Phospholipase D1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PLD1 Western Blot GuideDesigning an IHC experiment for Phospholipase D1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PLD1 IHC GuidePLD1 Infographic by Boster Bio
All PLD1 Products
Product
Figures
Specificity
Applications
Price
Anti-PLD2 Picoband® Antibody
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A02586
100 μg/vial
Cat # A02586
100 μg/vial
Anti-Phospholipase D1/PLD1 Antibody Picoband®
1 Citations
Human, Mouse
WB
$370
Cat # PB9380
100 μg/vial
Cat # PB9380
100 μg/vial
PLD1 Overview
Facts about Phospholipase D1.
Phospholipase D1 (PLD1)
Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PLD1 |
| Uniprot: | Q13393 |
| Entrez: | 5337 |
Family
| Belongs to: |
|---|
| phospholipase D family |
Alternative Names
Choline phosphatase 1; EC 3.1.4.4; hPLD1; Phosphatidylcholine-hydrolyzing phospholipase D1; phospholipase D1; phospholipase D1, phophatidylcholine-specific; phospholipase D1, phosphatidylcholine-specific; PLD 1; PLD1
Molecular Weight
Mass (kDA):
124.184 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q26.31 |
| Sequence: | 3; NC_000003.12 (171600404..171810483, complement) |
Tissue Specificity
Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine.
Subcellular Localizations
Cytoplasm, perinuclear region. Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Late endosome membrane; Lipid-anchor; Cytoplasmic side.
Diseases
- Malignant Neoplasms
- Neoplasms
- Tissue Adhesions
- Pertussis
- Cell Transformation, Neoplastic
- Inflammation
- Cell Invasion
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Carcinoma
- Mammary Neoplasms
- Hyperplasia
- Neoplasm Invasiveness
Interacting Proteins
- CFL1
- RHEB
Pathways
- Secretion
- Localization
- Exocytosis
- Transport
- Cell Proliferation
- Cell Migration
- Cell Growth
- Endocytosis
- Membrane Fusion
- Pathogenesis
- Phagocytosis
- Chemotaxis
- Cell Cycle
PTMs
- Phosphorylation
- Ribosylation
- Cleavage
- Myristoylation
- Palmitoylation
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLD1
bosterbio.com/bosterbio-gene-info-cards/PLD1
References
PMID: 8530346 by Hammond S.M., et al. Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family.
PMID: 9013646 by Hammond S.M., et al. Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5- bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP- binding proteins and protein kinase C-alpha.