Phospholipase D1 Antibodies

AND PLD1 ELISA kits, Phospholipase D1 Proteins

Many biological assays use antibodies to detect Phospholipase D1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Phospholipase D1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Phospholipase D1 antibodies...

We validate the specificity of these antibodies to Phospholipase D1 by testing them on tissues known to express PLD1 positively and negatively. Browse below to find the PLD1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLD1 Infographic by Boster Bio

All PLD1 Products

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Applications

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Anti-Phospholipase D1/PLD1 Antibody Picoband®

1 Citations 3 Q&As

Anti-PLD1 Picoband antibody, PB9380, Western blottingAll lanes: Anti PLD1 (PB9380) at 0

Human, Mouse

$370
Cat # PB9380
100 μg/vial

Anti-Phospho PLD1 (Ser561) Antibody

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using PLD1 (Phospho-Ser561) Antibody

Immunofluorescence analysis of HepG2 cells, using PLD1 (Phospho-Ser561) Antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using PLD1 (Phospho-Ser561) Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC

$335
Cat # P02031
100ul

Anti-PLD1/Phospholipase D1 Antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PLD1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC

$335
Cat # A02031
100ul

Anti-Phospho-PC-PLD1 (T147) Antibody

Western Blot analysis of 1 Hela, 2 treated with LPS 100ng/mL 20mim, using primary antibody at 1:1000 dilution

Immunohistochemical analysis of paraffin-embedded human liver cancer

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A02031T147
100ul

Anti-Phospho-PC-PLD1 (S561) Antibody

Human, Mouse, Rat

ELISA, IF, IHC

$380
Cat # A02031S561
100ul

PLD1 Overview

Facts about Phospholipase D1.

PLD1 3D structure. Source: alphafold

Phospholipase D1 (PLD1)

Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity).

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Gene Information

Human
Gene Name:	PLD1
Uniprot:	Q13393
Entrez:	5337

Family

Belongs to:

phospholipase D family

Alternative Names

Choline phosphatase 1; EC 3.1.4.4; hPLD1; Phosphatidylcholine-hydrolyzing phospholipase D1; phospholipase D1; phospholipase D1, phophatidylcholine-specific; phospholipase D1, phosphatidylcholine-specific; PLD 1; PLD1

Molecular Weight

Mass (kDA):
124.184 kDA

Genomic Context


Human

Location:	3q26.31
Sequence:	3; NC_000003.12 (171600404..171810483, complement)

Tissue Specificity

Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine.

Subcellular Localizations

Cytoplasm, perinuclear region. Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Late endosome membrane; Lipid-anchor; Cytoplasmic side.

Diseases

Malignant Neoplasms
Neoplasms
Tissue Adhesions
Pertussis
Cell Transformation, Neoplastic
Inflammation
Cell Invasion
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Carcinoma
Mammary Neoplasms
Hyperplasia
Neoplasm Invasiveness

Leukemia
Diabetes Mellitus
Melanoma
Pheochromocytoma
Nervousness
Autoimmune Reaction
Hypoxia

Interacting Proteins

CFL1
RHEB

Pathways

Secretion
Localization
Exocytosis
Transport
Cell Proliferation
Cell Migration
Cell Growth
Endocytosis
Membrane Fusion
Pathogenesis
Phagocytosis
Chemotaxis
Cell Cycle

Cell Death
Vesicle Transport
Angiogenesis
Rna Interference
Cell Adhesion
Glucose Transport
Intracellular Signal Transduction

PTMs

Phosphorylation
Ribosylation
Cleavage
Myristoylation
Palmitoylation

Dephosphorylation
Acylation
Glycosylation
Acetylation
Geranylgeranylation

Ubiquitination

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLD1

References

PMID: 8530346 by Hammond S.M., et al. Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family.

PMID: 9013646 by Hammond S.M., et al. Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5- bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP- binding proteins and protein kinase C-alpha.