- Table of Contents
Pol-delta4 participates in Okazaki fragment processing, through both the short flap pathway, in addition to a nick translation system (PubMed:24035200). Under conditions of DNA replication stress, required for the treatment of broken replication forks through break- induced replication (BIR), a mechanism which may induce segmental genomic duplications of up to 200 kb (PubMed:24310611).
|DNA polymerase delta subunit 4 family|
|Sequence:||11; NC_000011.10 (67350765..67353596, complement)|
Nucleus. Partially recruited to DNA damage sites within 2 hours following UV irradiation, before degradation.