POMT1 Antibodies

AND POMT1 ELISA kits, POMT1 Proteins

Many biological assays use antibodies to detect POMT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POMT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POMT1 antibodies...

We validate the specificity of these antibodies to POMT1 by testing them on tissues known to express POMT1 positively and negatively. Browse below to find the POMT1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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POMT1 Infographic by Boster Bio

All POMT1 Products

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Product

Figures

Specificity

Applications

Price

Anti-POMT1 Antibody

Western blot analysis of extracts of various cell lines, using POMT1 antibody at 1:1000 dilution

Human, Mouse

$405
Cat # A04295
100ul

POMT1 (NM_001077366) Human Over-expression Lysate

Human

$628
Cat # LS010585
20 µg, 100 µg

Anti-POMT1 Antibody Picoband®

Western blot analysis of POMT1 using anti-POMT1 antibody (A04295-1)

Flow Cytometry analysis of MCF-7 cells using anti-POMT1 antibody (A04295-1)

Human, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A04295-1
100 μg/vial

POMT1 Overview

Facts about Protein O-mannosyl-transferase 1.

POMT1 3D structure. Source: alphafold

Protein O-mannosyl-transferase 1 (POMT1)

Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient.

Gene Information

Human
Gene Name:	POMT1
Uniprot:	Q9Y6A1
Entrez:	10585

Family

Belongs to:

glycosyltransferase 39 family

Alternative Names

Dolichyl-phosphate-mannose--protein mannosyltransferase 1; EC 2.4.1; EC 2.4.1.109; FLJ37239; LGMD2K; MDDGA1; MDDGB1; MDDGC1; protein O-mannosyl-transferase 1; protein-O-mannosyltransferase 1; RT

Molecular Weight

Mass (kDA):
84.881 kDA

Genomic Context


Human

Location:	9q34.13
Sequence:	9; NC_000009.12 (131502902..131523803)

Tissue Specificity

Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Muscular Dystrophy
Dystrophy
Walker-warburg Congenital Muscular Dystrophy
Congenital Muscular Dystrophy (disorder)
Eye Abnormalities
Coronary Microvascular Disease
Muscle Eye Brain Disease
Lissencephaly
Congenital Anomaly Of Brain
Muscular Dystrophies, Limb-girdle
Fukuyama Type Congenital Muscular Dystrophy
Weakness

Muscle Weakness
Nervousness
Hydrocephalus
Microcephaly
Cobblestone Lissencephaly
Alpha-dystroglycanopathies

Pathways

Glycosylation
Protein Glycosylation
Rna Interference
Localization
Aging
Brain Development
Synaptic Transmission
Muscle Contraction
Embryo Development
Eclosion
Flight
Neuron Migration

Mrna Splicing
Muscle Attachment
Protein Folding
Locomotion
Rna Processing
Pathogenesis

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POMT1

References

PMID: 10366449 by Perez Jurado L.A., et al. Identification of a human homolog of the Drosophila rotated abdomen gene (POMT1) encoding a putative protein O-mannosyl-transferase, and assignment to human chromosome 9q34.1.

PMID: 12369018 by Beltran-Valero de Bernabe D., et al. Mutations in the O-mannosyltransferase gene POMT1 give rise to the severe neuronal migration disorder Walker-Warburg syndrome.