Prostaglandin E2 receptor EP1 subtype (PTGER1)

Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins that activate a phosphatidylinositol-calcium second messenger system.

May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in a variety of tissues.