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Facts about Prostaglandin E2 receptor EP1 subtype.
May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in a variety of tissues.
| Human | |
|---|---|
| Gene Name: | PTGER1 |
| Uniprot: | P34995 |
| Entrez: | 5731 |

| Belongs to: |
|---|
| G-protein coupled receptor 1 family |

EP1; PGE receptor EP1 subtype; PGE receptor, EP1 subtype; PGE2 receptor EP1 subtype; prostaglandin E receptor 1 (subtype EP1), 42kD; prostaglandin E receptor 1 (subtype EP1), 42kDa; prostaglandin E receptor 1, subtype EP1; prostaglandin E2 receptor EP1 subtype; Prostanoid EP1 receptor; PTGER1
Mass (kDA):
41.801 kDA

| Human | |
|---|---|
| Location: | 19p13.12 |
| Sequence: | 19; NC_000019.10 (14472466..14475354, complement) |
Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart.
Cell membrane; Multi-pass membrane protein.





PMID: 8253813 by Funk C.D., et al. Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype.