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- Table of Contents
PTGES2 Antibodies
AND PTGES2 ELISA kits, PTGES2 Proteins
Many biological assays use antibodies to detect PTGES2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTGES2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTGES2 antibodies...
Designing a Western blot for PTGES2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PTGES2 Western Blot GuideDesigning an IHC experiment for PTGES2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PTGES2 IHC GuidePTGES2 Infographic by Boster Bio
All PTGES2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06706-2
100 μg/vial
Cat # A06706-2
100 μg/vial
PTGES2 Overview
Facts about Prostaglandin E synthase 2.
Prostaglandin E synthase 2 (PTGES2)
Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2). .
Gene Information
| Human | |
|---|---|
| Gene Name: | PTGES2 |
| Uniprot: | Q9H7Z7 |
| Entrez: | 80142 |
Family
| Belongs to: |
|---|
| GST superfamily |
Alternative Names
C9orf15; chromosome 9 open reading frame 15; EC 5.3.99.3; FLJ14038; gamma-interferon-activated transcriptional element-binding factor 1; GATE-binding factor 1; GBF1; membrane-associated prostaglandin E synthase 2; Microsomal prostaglandin E synthase 2; microsomal prostaglandin E synthase-2; mPGES2; mPGES-2; PGES2; PGES2MGC11289; prostaglandin E synthase 2; PTGES2
Molecular Weight
Mass (kDA):
41.943 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q34.11 |
| Sequence: | 9; NC_000009.12 (128120693..128128462, complement) |
Tissue Specificity
Widely expressed. Expressed in the heart, including apex, inter-ventricular septum, both atria and ventricles, but not in the aorta. Also expressed in fetal heart. Detected in various regions of the brain: cerebellum; occipital, frontal and parietal lobes. Also expressed in the lymph nodes, skeletal muscle, kidney and trachea, but not in the thymus or lung. Overexpressed in colorectal cancer.
Subcellular Localizations
Golgi apparatus membrane; Single-pass membrane protein.; [Prostaglandin E synthase 2 truncated form]: Cytoplasm, perinuclear region. Synthesized as a Golgi membrane-bound protein, which is further cleaved into the predominant soluble truncated form. The truncated form is cytoplasmic and is enriched in the perinuclear region.
Diseases
- Malignant Neoplasms
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Endometrial Polyp
- Neoplasms
- Adenocarcinoma
- Obesity
- Malignant Neoplasm Of Breast
- Choline Deficiency
- Endometrial Adenocarcinoma
- Endometrial Neoplasms
- Hypoxia
Interacting Proteins
- C1orf189
Pathways
- Methylation
- Decidualization
- Cell Proliferation
- Parturition
- Fertilization
- Dna Methylation
- Angiogenesis
- Pathogenesis
PTMs
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTGES2
bosterbio.com/bosterbio-gene-info-cards/PTGES2
References
PMID: 11866447 by Tanikawa N., et al. Identification and characterization of a novel type of membrane- associated prostaglandin E synthase.
PMID: 12804604 by Watanabe K., et al. Essential 110Cys in active site of membrane-associated prostaglandin E synthase-2.