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- Table of Contents
Facts about RB1-inducible coiled-coil protein 1.
typhimurium infection and following xenophagy (By similarity). Involved in repair of DNA damage caused by ionizing radiation, which then improves cell survival by decreasing apoptosis (By similarity).
| Human | |
|---|---|
| Gene Name: | RB1CC1 |
| Uniprot: | Q8TDY2 |
| Entrez: | 9821 |

| Belongs to: |
|---|
| ATG17 family |

CC1; DRAGOU14; FIP200; KIAA0203200 kDa FAK family kinase-interacting protein; RB1-inducible coiled-coil 1; RB1-inducible coiled-coil protein 1; RBICC
Mass (kDA):
183.091 kDA

| Human | |
|---|---|
| Location: | 8q11.23 |
| Sequence: | 8; NC_000008.11 (52622458..52714466, complement) |
Expression levels correlated closely with those of RB1 in cancer cell lines as well as in various normal human tissues. Abundantly expressed in human musculoskeletal and cultured osteosarcoma cells.
Nucleus. Cytoplasm. Cytoplasm, cytosol. Preautophagosomal structure. Lysosome. Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane that sequesters a portion of the cytoplasm resulting in the formation of an autophagosome.






PMID: 11850849 by Chano T., et al. Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells.
PMID: 10769033 by Ueda H., et al. Suppression of Pyk2 kinase and cellular activities by FIP200.