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- Table of Contents
1 Citations
Facts about Rapamycin-insensitive companion of mTOR.
MTORC2 seems to work upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. MTORC2 promotes the serum-induced formation of stress-fibers or F-actin.
| Mouse | |
|---|---|
| Gene Name: | Rictor |
| Uniprot: | Q6QI06 |
| Entrez: | 78757 |

| Belongs to: |
|---|
| RICTOR family |

AVO3 homolog; AVO3; hAVO3; KIAA1999DKFZp686B11164; mAVO3; MGC39830; PIA; Pianissimo; rapamycin-insensitive companion of mTOR; Rictor; RPTOR independent companion of MTOR, complex 2; TORC2-specific protein AVO3
Mass (kDA):
191.57 kDA

| Mouse | |
|---|---|
| Location: | 15|15 A1 |
| Sequence: | 15; |




PMID: 15467718 by Jacinto E., et al. Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
PMID: 16962829 by Shiota C., et al. Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability.