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- Table of Contents
1 Citations
Facts about Sphingosine 1-phosphate receptor 3.
When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. .
| Human | |
|---|---|
| Gene Name: | S1PR3 |
| Uniprot: | Q99500 |
| Entrez: | 1903 |

| Belongs to: |
|---|
| G-protein coupled receptor 1 family |

EDG3; EDG-3; EDG3FLJ37523; Endothelial differentiation G-protein coupled receptor 3; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3; FLJ93220; G protein-coupled receptor, endothelial differentiation gene-3; LPB3; MGC71696; S1P receptor 3; S1P receptor EDG3; S1P receptor Edg-3; S1P3; S1PR3; sphingosine 1-phosphate receptor 3; Sphingosine 1-phosphate receptor Edg-3; sphingosine-1-phosphate receptor 3
Mass (kDA):
42.25 kDA

| Human | |
|---|---|
| Location: | 9q22.1 |
| Sequence: | 9; NC_000009.12 (88991468..89005155) |
Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.
Cell membrane; Multi-pass membrane protein.






PMID: 8878560 by Yamaguchi F., et al. Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9.
PMID: 9409733 by An S., et al. Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids.