Septin-5 Antibodies

AND SEPTIN5 ELISA kits, Septin-5 Proteins

Many biological assays use antibodies to detect Septin-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Septin-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Septin-5 antibodies...

We validate the specificity of these antibodies to Septin-5 by testing them on tissues known to express SEPTIN5 positively and negatively. Browse below to find the SEPTIN5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SEPTIN5 Infographic by Boster Bio

All SEPTIN5 Products

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Product

Figures

Specificity

Applications

Price

SEPTIN5 (NM_002688) Human Recombinant Protein

Coomassie blue staining of purified SEPTIN5 protein

$1062
Cat # PROTQ99719
20 µg

Anti-SEPT5/SEPTIN5 Antibody Picoband®

Western blot analysis of SEPT5/SEPTIN5 using anti-SEPT5/SEPTIN5 antibody (A11138)

Flow Cytometry analysis of K562 cells using anti-SEPT5/SEPTIN5 antibody (A11138)

Flow Cytometry analysis of NRK cells using anti-SEPT5/SEPTIN5 antibody (A11138)

Human, Rat

Flow Cytometry, WB

$370
Cat # A11138
100 μg/vial

SEPTIN5 (NM_002688) Human Over-expression Lysate

Human

$628
Cat # LS005413
20 µg, 100 µg

SEPTIN5 Overview

Facts about Septin-5.

SEPTIN5 3D structure. Source: alphafold

Septin-5 (SEPTIN5)

Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).

May play a role in platelet secretion (By similarity). .

Gene Information

Human
Gene Name:	SEPTIN5
Uniprot:	Q99719
Entrez:	5413

Family

Belongs to:

TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily

Alternative Names

CDCREL; CDCREL1; CDCREL-1; cell division control related protein 1; Cell division control-related protein 1; HCDCREL-1; peanut-like 1 (Drosophila); peanut-like 1; Peanut-like protein 1; platelet glycoprotein Ib beta chain; PNUTL1H5; septin 5; septin-5

Molecular Weight

Mass (kDA):
42.777 kDA

Genomic Context


Human

Location:	22q11.21
Sequence:	22; NC_000022.11 (19714503..19723319)

Tissue Specificity

Expressed at high levels in the CNS, as well as in heart and platelets (at protein level).

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton. In platelets, found in areas surrounding alpha-granules.

Diseases

Parkinson Disease
Neoplasms
Neurodegenerative Disorders
Juvenile Parkinson's Disease
Secondary Parkinson Disease
Leukemia
Nervousness
Malignant Neoplasms
Myeloid Leukemia
Digeorge Syndrome
Nerve Degeneration
Nervous System Disorder
Schizophrenia

Neurotoxicity Syndromes
Autistic Disorder
Dysplasia
Hemorrhage
Anxiety Disorders
Neuropathology Disease
Chromosomal Translocation

Interacting Proteins

MAGEA2

Pathways

Cytokinesis
Exocytosis
Secretion
Cell Division
Localization
Pathogenesis
Transport
Synaptic Transmission
Cell Death
Platelet Aggregation
Serotonin Secretion
Hemostasis
Oncogenesis

Vesicle Transport
Hyperphosphorylation
Regulation Of Signaling
Proteolysis
Synaptic Vesicle Transport
Serotonin Transport
Translation

PTMs

Phosphorylation

Ubiquitination

Cleavage

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SEPTIN5

References

PMID: 9022087 by Zieger B., et al. Alternative expression of platelet glycoprotein Ib(beta) mRNA from an adjacent 5' gene with an imperfect polyadenylation signal sequence.

PMID: 9385360 by McKie J., et al. A human gene similar to Drosophila melanogaster peanut maps to the DiGeorge syndrome region of 22q11.