SIRT7 Antibodies

AND SIRT7 ELISA kits, SIRT7 Proteins

Many biological assays use antibodies to detect SIRT7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SIRT7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SIRT7 antibodies...

We validate the specificity of these antibodies to SIRT7 by testing them on tissues known to express SIRT7 positively and negatively. Browse below to find the SIRT7 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SIRT7 Infographic by Boster Bio

All SIRT7 Products

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Anti-SIRT7 Antibody Picoband®

2 Citations 5 Q&As

Western blot analysis of SIRT7 using anti-SIRT7 antibody (PB9358)

IHC analysis of SIRT7 using anti-SIRT7 antibody (PB9358)

Human, Mouse, Rat

IHC, WB

$370
Cat # PB9358
100 μg/vial

SIRT7 (NM_016538) Human Over-expression Lysate

Human

$628
Cat # LS051547
20 µg, 100 µg

Anti-SIRT7 Antibody (Monoclonal, 34S18)

Human, Mouse, Rat

ChIP, IP, IF, IHC, ICC, WB

$370
Cat # M03022
100 μl/vial

SIRT7 Overview

Facts about NAD-dependent protein deacetylase sirtuin-7.

NAD-dependent protein deacetylase sirtuin-7 (SIRT7)

NAD-dependent protein deacetylase that specifically mediates deacetylation of histone H3 at'Lys-18' (H3K18Ac). Compared to other histone deacetylases, displays selectivity for one histone mark, H3K18Ac, directly linked to control of gene expression.

H3K18Ac is mainly present around the transcription start site of genes and has been associated with activation of nuclear hormone receptors. SIRT7 thereby functions as a transcription repressor.

Gene Information

Human
Gene Name:	SIRT7
Uniprot:	Q9NRC8
Entrez:	51547

Family

Belongs to:

sirtuin family

Alternative Names

EC 3.5.1.-; MGC126840; MGC126842; silent mating type information regulation 2, S.cerevisiae, homolog 7; SIR2L7NAD-dependent deacetylase sirtuin-7; SIR2-like protein 7; sir2-related protein type 7; sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae); sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 7; sirtuin 7; sirtuin type 7

Molecular Weight

Mass (kDA):
44.898 kDA

Genomic Context


Human

Location:	17q25.3
Sequence:	17; NC_000017.11 (81911939..81918176, complement)

Subcellular Localizations

Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome. Cytoplasm. Mainly localizes in the nucleolus and nucleoplasm (PubMed:24207024, PubMed:28886238, PubMed:28790157, PubMed:31075303). Associated with rDNA promoter and transcribed region (PubMed:16079181, PubMed:19174463). Associated with nucleolar organizer regions during mitosis (PubMed:16079181, PubMed:19174463). In response to stress, released from nucleolus to nucleoplasm (PubMed:24207024). Associated with chromatin (PubMed:22722849). In response to DNA damage, recruited to DNA double-strand breaks (DSBs) sites (PubMed:27436229) (Probable