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- Table of Contents
1 Citations 10 Q&As
Facts about Excitatory amino acid transporter 2.
Mediates Cl(-) flux that's not coupled to amino acid transport; this avoids the accumulation of negative charges because of aspartate and Na(+) symport (PubMed:14506254). Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate (By similarity).
| Human | |
|---|---|
| Gene Name: | SLC1A2 |
| Uniprot: | P43004 |
| Entrez: | 6506 |

| Belongs to: |
|---|
| dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family |

EAAT2; GLT1; member 2; SLC1A2; solute carrier family 1 (glial high affinity glutamate transporter), member 2; Solute carrier family 1 member 2
Mass (kDA):
62.104 kDA

| Human | |
|---|---|
| Location: | 11p13 |
| Sequence: | 11; NC_000011.10 (35251205..35420058, complement) |
Cell membrane; Multi-pass membrane protein.






PMID: 7521911 by Arriza J.L., et al. Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex.
PMID: 8172925 by Shashidharan P., et al. Molecular cloning of human brain glutamate/aspartate transporter II.
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